Vibramycin and Death - a phase IV clinical study of FDA data

Summary:

Death is reported as a side effect among people who take Vibramycin (doxycycline), especially for people who are male, 60+ old, have been taking the drug for 1 - 6 months also take Zolpidem, and have Multiple myeloma.

The study is created by eHealthMe based on reports of 1,632 people who have side effects when taking Vibramycin from the FDA, and is updated regularly.

What is Vibramycin?

Vibramycin has active ingredients of doxycycline. It is often used in acne. eHealthMe is studying from 1,692 Vibramycin users. Check the latest studies of Vibramycin.

On Jul, 12, 2026

1,632 people reported to have side effects when taking Vibramycin.
Among them, 23 people (1.41%) died.

Among these 23 people:

How long have people been on Vibramycin when they died? *

What is the gender of people who died when taking Vibramycin? *

female: 20 %
male: 80 %

What is the age of people who died when taking Vibramycin? *

What are other drugs people take besides Vibramycin? *

What are other side effects people have before they died? *

Acute Kidney Failure: 10 people, 43.48%
Emotional Distress: 9 people, 39.13%
Stress And Anxiety: 9 people, 39.13%
Dizziness: 8 people, 34.78%
Anaemia (lack of blood): 8 people, 34.78%
Pain: 8 people, 34.78%
Paleness (unusual lightness of skin colour): 7 people, 30.43%
General Physical Health Deterioration (weak health status): 7 people, 30.43%
Gait Disturbance: 7 people, 30.43%
Fever: 7 people, 30.43%

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 6 people, 26.09%
Urge Incontinence (urinary incontinence): 2 people, 8.70%
Femoral Neck Fracture (neck of femur bone fracture): 2 people, 8.70%
Bone Formation Decreased: 2 people, 8.70%
Stomatitis (inflammation of mucous membrane of mouth): 2 people, 8.70%
Pertussis (whooping cough: a disease of the respiratory mucous membrane): 2 people, 8.70%
Thrombosis (formation of a blood clot inside a blood vessel): 2 people, 8.70%
Hiv Infection: 2 people, 8.70%
General Anaesthesia: 2 people, 8.70%
Colon Cancer: 1 person, 4.35%

* Approximation only. Some reports may have incomplete information.

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Vibramycin:

Vibramycin (1,692 reports)

Expand to all the drugs that have ingredients of doxycycline:

Death and drugs with ingredients of doxycycline (21 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Vibramycin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Death:

Death (3,128 drugs)

Browse all the conditions that are associated with Death:

Death (3,686 conditions)

Related publications that referenced our studies

Dmour HH, Zayadeen AR, Shawagfeh JS, "Effect of Long Term Prophylaxis of Antimalarial Drug (Doxycycline) on Liver Span by Ultrasound", Middle East Journal of Internal Medicine, 2013 Jan .
Dmour HH, Zayadeen AR, Shawagfeh JS, "Effect of Long Term Prophylaxis of Antimalarial Drug (Doxycycline) on Liver Span by Ultrasound", Middle East Journal of Internal Medicine, 2013 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on doxycycline (the active ingredients of Vibramycin) and Vibramycin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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