Vicoprofen and Retinopathy - a phase IV clinical study of FDA data

Summary:

Retinopathy is reported as a side effect among people who take Vicoprofen (hydrocodone bitartrate; ibuprofen), especially for people who are female, 40-49 old, also take Vicodin, and have Bone pain.

The phase IV clinical study analyzes which people have Retinopathy when taking Vicoprofen. It is created by eHealthMe based on reports of 1,635 people who have side effects when taking Vicoprofen from the FDA, and is updated regularly.

What is Vicoprofen?

Vicoprofen has active ingredients of hydrocodone bitartrate; ibuprofen. It is often used in pain. eHealthMe is studying from 1,842 Vicoprofen users. Check the latest studies of Vicoprofen.

What is Retinopathy?

Retinopathy (acute damage to the retina of the eye) is found to be associated with 442 drugs and 494 conditions by eHealthMe. Check the latest studies of Retinopathy.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 29, 2026

1,635 people reported to have side effects when taking Vicoprofen.
Among them, 18 people (1.1%) have Retinopathy.

Among these 18 people:

What is the gender of people who have Retinopathy when taking Vicoprofen? *

female: 80 %
male: 20 %

What is the age of people who have Retinopathy when taking Vicoprofen? *

What are other drugs people take besides Vicoprofen? *

What are other side effects people have besides Retinopathy? *

Wound Infection Staphylococcal: 18 people, 100.00%
Intervertebral Disc Degeneration (spinal disc degeneration): 18 people, 100.00%
Gingival Disorder (gum disease): 18 people, 100.00%
Gingival Pain (gum pain): 18 people, 100.00%
Hepatic Steatosis (fatty liver disease): 18 people, 100.00%
Hot Flush (sudden feelings of heat): 18 people, 100.00%
Hypoglycemia (low blood sugar): 18 people, 100.00%
Hypokalemia (low potassium): 18 people, 100.00%
Intervertebral Disc Protrusion (spinal disc protrusion): 18 people, 100.00%
Fever: 18 people, 100.00%

What are the existing conditions these people have? *

Metastases To Bone (cancer spreads to bone): 18 people, 100.00%
High Blood Pressure: 18 people, 100.00%
Diabetes: 18 people, 100.00%
Depression: 18 people, 100.00%
Breast Cancer: 18 people, 100.00%
Bone Pain: 18 people, 100.00%
Breast Cancer Metastatic: 1 person, 5.56%

* Approximation only. Some reports may have incomplete information.

Do you take Vicoprofen and have Retinopathy?

- Check whether Retinopathy is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Vicoprofen:

Vicoprofen (1,842 reports)

Retinopathy treatments and more:

Retinopathy (4,577 reports)

How severe was Retinopathy and when was it recovered:

Retinopathy in Vicoprofen

Expand to all the drugs that have ingredients of hydrocodone bitartrate; ibuprofen:

Retinopathy and drugs with ingredients of hydrocodone bitartrate; ibuprofen

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Vicoprofen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Retinopathy:

Retinopathy (442 drugs)

Browse all the conditions that are associated with Retinopathy:

Retinopathy (494 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on hydrocodone bitartrate; ibuprofen (the active ingredients of Vicoprofen) and Vicoprofen (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.