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Videx and Hyporeflexia - a phase IV clinical study of FDA data

Summary:

Hyporeflexia is reported as a side effect among people who take Videx (didanosine), especially for people who are male, 40-49 old, have been taking the drug for 6 - 12 months also take Zerit, and have Hiv infection.

The phase IV clinical study analyzes which people have Hyporeflexia when taking Videx. It is created by eHealthMe based on reports of 7,921 people who have side effects when taking Videx from the FDA, and is updated regularly.

What is Videx?

Videx has active ingredients of didanosine. eHealthMe is studying from 7,927 Videx users. Check the latest studies of Videx.

What is Hyporeflexia?

Hyporeflexia (a condition of below normal or absent reflexes) is found to be associated with 440 drugs and 594 conditions by eHealthMe. Check the latest studies of Hyporeflexia.

On Aug, 11, 2026

7,921 people reported to have side effects when taking Videx.
Among them, 22 people (0.28%) have Hyporeflexia.

Could Videx cause Hyporeflexia?

Among these 22 people:

How long have people been on Videx when they have Hyporeflexia? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 25 %
  • 6 - 12 months: 25 %
  • 1 - 2 years: 25 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 25 %
  • 10+ years: 0.0 %

What is the gender of people who have Hyporeflexia when taking Videx? *

  • female: 13.64 %
  • male: 86.36 %

What is the age of people who have Hyporeflexia when taking Videx? *

  • 0-1: 0.0 %
  • 2-9: 5 %
  • 10-19: 0.0 %
  • 20-29: 5 %
  • 30-39: 15 %
  • 40-49: 40 %
  • 50-59: 10 %
  • 60+: 25 %

What are other drugs people take besides Videx? *

  1. Zerit: 15 people, 68.18%
  2. Epivir: 9 people, 40.91%
  3. Norvir: 8 people, 36.36%
  4. Bactrim: 7 people, 31.82%
  5. Viracept: 7 people, 31.82%
  6. Lamivudine: 7 people, 31.82%
  7. Zidovudine: 6 people, 27.27%
  8. Viramune: 6 people, 27.27%
  9. Rimifon: 6 people, 27.27%
  10. Sustiva: 5 people, 22.73%

What are other side effects people have besides Hyporeflexia? *

  1. Weakness: 5 people, 22.73%
  2. Weight Decreased: 4 people, 18.18%
  3. Blood Lactate Dehydrogenase Increased: 4 people, 18.18%
  4. Pain In Limb: 4 people, 18.18%
  5. Nausea (feeling of having an urge to vomit): 4 people, 18.18%
  6. Muscle Atrophy (a decrease in the mass of the muscle): 4 people, 18.18%
  7. Lactic Acidosis (low ph in body tissues): 3 people, 13.64%
  8. Sleep Disorder: 3 people, 13.64%
  9. Cryptococcosis (potentially fatal fungal disease): 3 people, 13.64%
  10. Polyneuropathy (neurological disorder that occurs when many peripheral nerves throughout the body malfunction simultaneously): 3 people, 13.64%

What are the existing conditions these people have? *

  1. Hiv Infection: 7 people, 31.82%
  2. Tuberculosis (a bacterial infection by mycobacterium tuberculosis): 1 person, 4.55%
  3. High Blood Pressure: 1 person, 4.55%

* Approximation only. Some reports may have incomplete information.

Do you take Videx and have Hyporeflexia?

- Check whether Hyporeflexia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Videx:

Hyporeflexia treatments and more:

How severe was Hyporeflexia and when was it recovered:

Expand to all the drugs that have ingredients of didanosine:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Videx:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hyporeflexia:

Browse all the conditions that are associated with Hyporeflexia:

How the study uses the data?

The study uses data from the FDA. It is based on didanosine (the active ingredients of Videx) and Videx (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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