Vimovo and Sciatica - a phase IV clinical study of FDA data

Summary:

Sciatica is reported as a side effect among people who take Vimovo (esomeprazole magnesium; naproxen), especially for people who are female, 40-49 old, have been taking the drug for 6 - 12 months also take Humira, and have Fibromyalgia.

The phase IV clinical study analyzes which people have Sciatica when taking Vimovo. It is created by eHealthMe based on reports of 9,495 people who have side effects when taking Vimovo from the FDA, and is updated regularly.

What is Vimovo?

Vimovo has active ingredients of esomeprazole magnesium; naproxen. It is often used in osteoarthritis. eHealthMe is studying from 9,608 Vimovo users. Check the latest studies of Vimovo.

What is Sciatica?

Sciatica (a set of symptoms including pain caused by general compression or irritation of one of five spinal nerve roots of each sciatic nerve) is found to be associated with 1,152 drugs and 1,415 conditions by eHealthMe. Check the latest studies of Sciatica.

On Jul, 25, 2025

9,495 people reported to have side effects when taking Vimovo.
Among them, 14 people (0.15%) have Sciatica.

Among these 14 people:

How long have people been on Vimovo when they have Sciatica? *

What is the gender of people who have Sciatica when taking Vimovo? *

female: 70 %
male: 30 %

What is the age of people who have Sciatica when taking Vimovo? *

What are other drugs people take besides Vimovo? *

Xeljanz: 9 people, 64.29%
Pantoprazole: 9 people, 64.29%
Naproxen: 9 people, 64.29%
Methylprednisolone Sodium Succinate: 9 people, 64.29%
Methylprednisolone Acetate: 9 people, 64.29%
Meloxicam: 9 people, 64.29%
Lyrica: 9 people, 64.29%
Leflunomide: 9 people, 64.29%
Imuran: 9 people, 64.29%
Humira: 9 people, 64.29%

What are other side effects people have besides Sciatica? *

Hypoaesthesia (reduced sense of touch or sensation): 11 people, 78.57%
Drug Ineffective: 11 people, 78.57%
Drug Hypersensitivity: 11 people, 78.57%
Fatigue (feeling of tiredness): 10 people, 71.43%
Infusion Related Reaction: 9 people, 64.29%
Road Traffic Accident: 9 people, 64.29%
High Blood Pressure: 9 people, 64.29%
Sinusitis (inflammation of sinus): 9 people, 64.29%
Drug Intolerance (drug sensitivity): 9 people, 64.29%
Sleep Disorder: 9 people, 64.29%

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 9 people, 64.29%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 9 people, 64.29%
Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder): 9 people, 64.29%
Inflammation: 9 people, 64.29%
Fibromyalgia (a long-term condition which causes pain all over the body): 9 people, 64.29%
Indigestion: 2 people, 14.29%
Cellulitis (infection under the skin): 2 people, 14.29%
Sleep Disorder: 2 people, 14.29%
Swelling: 1 person, 7.14%
Gastritis Erosive (a break in the surface layer of the membrane lining the stomach with infection): 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Vimovo and have Sciatica?

- Check whether Sciatica is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Vimovo:

Vimovo (9,608 reports)

Sciatica treatments and more:

Sciatica (28,503 reports)

How severe was Sciatica and when was it recovered:

Sciatica in Vimovo

Expand to all the drugs that have ingredients of esomeprazole magnesium; naproxen:

Sciatica and drugs with ingredients of esomeprazole magnesium; naproxen

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Vimovo:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Sciatica:

Sciatica (1,152 drugs)

Browse all the conditions that are associated with Sciatica:

Sciatica (1,415 conditions)

Drugs similar to Vimovo and Sciatica :

How the study uses the data?

The study uses data from the FDA. It is based on esomeprazole magnesium; naproxen (the active ingredients of Vimovo) and Vimovo (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.