Vimpat and Angioedema - a phase IV clinical study of FDA data

Summary:

Angioedema is reported as a side effect among people who take Vimpat (lacosamide), especially for people who are female, 20-29 old, have been taking the drug for < 1 month also take Keppra, and have Status epilepticus.

The phase IV clinical study analyzes which people have Angioedema when taking Vimpat. It is created by eHealthMe based on reports of 20,279 people who have side effects when taking Vimpat from the FDA, and is updated regularly.

What is Vimpat?

Vimpat has active ingredients of lacosamide. It is often used in epilepsy. eHealthMe is studying from 20,831 Vimpat users. Check the latest studies of Vimpat.

What is Angioedema?

Angioedema (rapid swelling of the dermis) is found to be associated with 1,197 drugs and 2,089 conditions by eHealthMe. Check the latest studies of Angioedema.

On Apr, 21, 2026

20,279 people reported to have side effects when taking Vimpat.
Among them, 27 people (0.13%) have Angioedema.

Among these 27 people:

How long have people been on Vimpat when they have Angioedema? *

What is the gender of people who have Angioedema when taking Vimpat? *

female: 65.22 %
male: 34.78 %

What is the age of people who have Angioedema when taking Vimpat? *

What are other drugs people take besides Vimpat? *

What are other side effects people have besides Angioedema? *

Anaphylaxis (serious allergic reaction that is rapid in onset and may cause death): 3 people, 11.11%
Eosinophil Count Increased: 3 people, 11.11%
Vomiting Projectile: 2 people, 7.41%
Pain: 2 people, 7.41%
Body Temperature Increased: 2 people, 7.41%
Chills (felling of cold): 2 people, 7.41%
Drug Eruption (adverse drug reaction of the skin): 2 people, 7.41%
Ecchymosis (a discoloration of the skin resulting from bleeding underneath): 2 people, 7.41%
Erythema Multiforme (a type of hypersensitivity reaction): 2 people, 7.41%
Fainting (loss of consciousness and postural tone): 2 people, 7.41%

What are the existing conditions these people have? *

Status Epilepticus (a life-threatening condition in which the brain is in a state of persistent seizure): 4 people, 14.81%
Lung Adenocarcinoma (a form of non-small cell lung cancer): 3 people, 11.11%
Depression: 3 people, 11.11%
Pneumonia Aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree): 2 people, 7.41%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 7.41%
Grand Mal Convulsion (a type of generalized seizure that affects the entire brain): 2 people, 7.41%
Staphylococcal Infection (an infection with staphylococcus bacteria): 1 person, 3.70%
Partial Seizures (seizures which affect only a part of the brain at onset): 1 person, 3.70%
Chronic Thyroiditis (long lasting inflammation of thyroid gland): 1 person, 3.70%
Brain Neoplasm (tumour of brain): 1 person, 3.70%

* Approximation only. Some reports may have incomplete information.

Do you take Vimpat and have Angioedema?

- Check whether Angioedema is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Vimpat:

Vimpat (20,831 reports)

Angioedema treatments and more:

Angioedema (44,989 reports)

Browse all side effects of Vimpat:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Angioedema:

Angioedema (1,197 drugs)

Browse all the conditions that are associated with Angioedema:

Angioedema (2,089 conditions)

Related publications that referenced our studies

Banaga, Y., Mohmmed, K., Mustafa, H., & Barrett, J, "Angioedema 2 months after Administration of Rivaroxaban (Xarelto)", J Clin Case Rep, 2014 Jan .
Banaga, Y., Mohmmed, K., Mustafa, H., & Barrett, J, "Angioedema 2 months after Administration of Rivaroxaban (Xarelto)", J Clin Case Rep, 2014 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on lacosamide (the active ingredients of Vimpat) and Vimpat (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.