Vimpat and Atrioventricular block second degree - a phase IV clinical study of FDA data

Summary:

Atrioventricular block second degree is reported as a side effect among people who take Vimpat (lacosamide), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Keppra, and have Partial seizures.

The phase IV clinical study analyzes which people have Atrioventricular block second degree when taking Vimpat. It is created by eHealthMe based on reports of 20,279 people who have side effects when taking Vimpat from the FDA, and is updated regularly.

What is Vimpat?

Vimpat has active ingredients of lacosamide. It is often used in epilepsy. eHealthMe is studying from 20,831 Vimpat users. Check the latest studies of Vimpat.

What is Atrioventricular block second degree?

Atrioventricular block second degree (heart block second degree) is found to be associated with 377 drugs and 818 conditions by eHealthMe. Check the latest studies of Atrioventricular block second degree.

On Jul, 15, 2026

20,279 people reported to have side effects when taking Vimpat.
Among them, 48 people (0.24%) have Atrioventricular block second degree.

Could Vimpat cause Atrioventricular block second degree?

Among these 48 people:

How long have people been on Vimpat when they have Atrioventricular block second degree? *

What is the gender of people who have Atrioventricular block second degree when taking Vimpat? *

female: 43.48 %
male: 56.52 %

What is the age of people who have Atrioventricular block second degree when taking Vimpat? *

What are other drugs people take besides Vimpat? *

What are other side effects people have besides Atrioventricular block second degree? *

Irritability: 6 people, 12.50%
Stress And Anxiety: 6 people, 12.50%
Partial Seizures With Secondary Generalisation (partial seizure may spread within the brain, a process known as secondary generalization): 5 people, 10.42%
Bradycardia (abnormally slow heart action): 4 people, 8.33%
Atrioventricular Block First Degree (heart block first degree): 3 people, 6.25%
Urosepsis (secondary infection that occurs when a urinary tract infection spreads to the bloodstream): 3 people, 6.25%
Arrhythmias (irregular heartbeat): 3 people, 6.25%
Atrioventricular Block Complete (heart block complete): 2 people, 4.17%
Malaise (a feeling of general discomfort or uneasiness): 2 people, 4.17%
Mental Disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability): 2 people, 4.17%

What are the existing conditions these people have? *

Partial Seizures (seizures which affect only a part of the brain at onset): 7 people, 14.58%
Agitation (state of anxiety or nervous excitement): 3 people, 6.25%
Type 2 Diabetes: 2 people, 4.17%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 2 people, 4.17%
Dyslipidaemia (abnormal amount of lipids): 2 people, 4.17%
Psychotic Disorder: 2 people, 4.17%
High Blood Pressure: 2 people, 4.17%
Insomnia (sleeplessness): 2 people, 4.17%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 1 person, 2.08%
Cardiac Failure: 1 person, 2.08%

* Approximation only. Some reports may have incomplete information.

Do you take Vimpat and have Atrioventricular block second degree?

- Check whether Atrioventricular block second degree is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Vimpat:

Vimpat (20,831 reports)

Browse all side effects of Vimpat:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Atrioventricular block second degree:

Atrioventricular block second degree (377 drugs)

Browse all the conditions that are associated with Atrioventricular block second degree:

Atrioventricular block second degree (818 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on lacosamide (the active ingredients of Vimpat) and Vimpat (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.