Vimpat and Coma - a phase IV clinical study of FDA data

Summary:

Coma is reported as a side effect among people who take Vimpat (lacosamide), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Keppra, and have Convulsion.

The phase IV clinical study analyzes which people have Coma when taking Vimpat. It is created by eHealthMe based on reports of 20,279 people who have side effects when taking Vimpat from the FDA, and is updated regularly.

What is Vimpat?

Vimpat has active ingredients of lacosamide. It is often used in epilepsy. eHealthMe is studying from 20,829 Vimpat users. Check the latest studies of Vimpat.

What is Coma?

Coma (state of unconsciousness lasting more than six hours) is found to be associated with 2,897 drugs and 3,165 conditions by eHealthMe. Check the latest studies of Coma.

On Oct, 24, 2025

20,279 people reported to have side effects when taking Vimpat.
Among them, 114 people (0.56%) have Coma.

Among these 114 people:

How long have people been on Vimpat when they have Coma? *

What is the gender of people who have Coma when taking Vimpat? *

female: 61.32 %
male: 38.68 %

What is the age of people who have Coma when taking Vimpat? *

What are other drugs people take besides Vimpat? *

What are other side effects people have besides Coma? *

Drowsiness: 14 people, 12.28%
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 13 people, 11.40%
Status Epilepticus (a life-threatening condition in which the brain is in a state of persistent seizure): 11 people, 9.65%
Nausea And Vomiting: 9 people, 7.89%
Poisoning Deliberate: 8 people, 7.02%
Memory Loss: 8 people, 7.02%
Respiratory Acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease): 8 people, 7.02%
Nausea (feeling of having an urge to vomit): 8 people, 7.02%
Overdose: 6 people, 5.26%
Grand Mal Convulsion (a type of generalized seizure that affects the entire brain): 6 people, 5.26%

What are the existing conditions these people have? *

Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 7 people, 6.14%
Partial Seizures (seizures which affect only a part of the brain at onset): 6 people, 5.26%
Lennox-Gastaut Syndrome (epilepsy characterized by frequent seizures and different seizure types): 6 people, 5.26%
Status Epilepticus (a life-threatening condition in which the brain is in a state of persistent seizure): 5 people, 4.39%
Psychotic Disorder: 4 people, 3.51%
Pneumonia: 3 people, 2.63%
Nausea (feeling of having an urge to vomit): 3 people, 2.63%
Depression: 3 people, 2.63%
Pain: 3 people, 2.63%
Arteriovenous Malformation: 2 people, 1.75%

* Approximation only. Some reports may have incomplete information.

Do you take Vimpat and have Coma?

- Check whether Coma is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Vimpat:

Vimpat (20,829 reports)

Coma treatments and more:

Coma (57,420 reports)

Common Vimpat side effects:

Browse all side effects of Vimpat:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common drugs associated with Coma:

Browse all the drugs that are associated with Coma:

Coma (2,897 drugs)

Common conditions associated with Coma:

Browse all the conditions that are associated with Coma:

Coma (3,165 conditions)

Drugs similar to Vimpat and Coma :

How the study uses the data?

The study uses data from the FDA. It is based on lacosamide (the active ingredients of Vimpat) and Vimpat (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.