Vimpat and Dry eyes - a phase IV clinical study of FDA data

Summary:

Dry eyes is reported as a side effect among people who take Vimpat (lacosamide), especially for people who are female, 40-49 old, have been taking the drug for 5 - 10 years also take Baclofen, and have Depression.

The phase IV clinical study analyzes which people have Dry eyes when taking Vimpat. It is created by eHealthMe based on reports of 20,279 people who have side effects when taking Vimpat from the FDA, and is updated regularly.

What is Vimpat?

Vimpat has active ingredients of lacosamide. It is often used in epilepsy. eHealthMe is studying from 20,832 Vimpat users. Check the latest studies of Vimpat.

What is Dry eyes?

Dry eyes (lack of adequate tears) is found to be associated with 1,578 drugs and 2,055 conditions by eHealthMe. Check the latest studies of Dry eyes.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Jul, 15, 2026

20,279 people reported to have side effects when taking Vimpat.
Among them, 61 people (0.3%) have Dry eyes.

Could Vimpat cause Dry eyes?

Among these 61 people:

How long have people been on Vimpat when they have Dry eyes? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 25 %
  • 6 - 12 months: 25 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 50 %
  • 10+ years: 0.0 %

What is the gender of people who have Dry eyes when taking Vimpat? *

  • female: 77.19 %
  • male: 22.81 %

What is the age of people who have Dry eyes when taking Vimpat? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 4.26 %
  • 30-39: 4.26 %
  • 40-49: 68.09 %
  • 50-59: 6.38 %
  • 60+: 17.02 %

What are other drugs people take besides Vimpat? *

  1. Gabapentin: 24 people, 39.34%
  2. Allopurinol: 24 people, 39.34%
  3. Baclofen: 24 people, 39.34%
  4. Ocrevus: 23 people, 37.70%
  5. Pantoprazole: 20 people, 32.79%
  6. Pantoprazole Sodium: 11 people, 18.03%
  7. Prednisone: 8 people, 13.11%
  8. Plaquenil: 8 people, 13.11%
  9. Singulair: 7 people, 11.48%
  10. Gabitril: 7 people, 11.48%

What are other side effects people have besides Dry eyes? *

  1. Fatigue (feeling of tiredness): 34 people, 55.74%
  2. Rashes (redness): 33 people, 54.10%
  3. Muscle Spasms (muscle contraction): 32 people, 52.46%
  4. Peripheral Swelling: 32 people, 52.46%
  5. High Blood Pressure: 32 people, 52.46%
  6. Heart Palpitations (feelings or sensations that your heart is pounding or racing): 31 people, 50.82%
  7. Weakness: 31 people, 50.82%
  8. Joint Pain: 30 people, 49.18%
  9. Balance Disorder: 29 people, 47.54%
  10. Rash Pruritic (redness with itching): 28 people, 45.90%

What are the existing conditions these people have? *

  1. Depression: 30 people, 49.18%
  2. Muscle Spasticity (tight or stiff muscles and an inability to control those muscles): 27 people, 44.26%
  3. Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 23 people, 37.70%
  4. Dermatitis Atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder): 7 people, 11.48%
  5. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 8.20%
  6. Stress And Anxiety: 4 people, 6.56%
  7. Waldenstrom's Macroglobulinaemia (cancer affects small lymphocytes (white blood cells)): 3 people, 4.92%
  8. Fibromyalgia (a long-term condition which causes pain all over the body): 3 people, 4.92%
  9. High Blood Pressure: 3 people, 4.92%
  10. Pain: 3 people, 4.92%

* Approximation only. Some reports may have incomplete information.

Do you take Vimpat and have Dry eyes?

- Check whether Dry eyes is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Vimpat:

Dry eyes treatments and more:

How severe was Dry eyes and when was it recovered:

Expand to all the drugs that have ingredients of lacosamide:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Vimpat:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Dry eyes:

Browse all the conditions that are associated with Dry eyes:


How the study uses the data?

The study uses data from the FDA. It is based on lacosamide (the active ingredients of Vimpat) and Vimpat (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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