Vimpat and Hyperkeratosis - a phase IV clinical study of FDA data

Summary:

Hyperkeratosis is reported as a side effect among people who take Vimpat (lacosamide), especially for people who are male, 60+ old, have been taking the drug for 1 - 6 months also take Pantoprazole, and have Metastatic malignant melanoma.

The phase IV clinical study analyzes which people have Hyperkeratosis when taking Vimpat. It is created by eHealthMe based on reports of 20,279 people who have side effects when taking Vimpat from the FDA, and is updated regularly.

What is Vimpat?

Vimpat has active ingredients of lacosamide. It is often used in epilepsy. eHealthMe is studying from 20,831 Vimpat users. Check the latest studies of Vimpat.

What is Hyperkeratosis?

Hyperkeratosis (thickening of the outer layer of the skin) is found to be associated with 780 drugs and 771 conditions by eHealthMe. Check the latest studies of Hyperkeratosis.

On Jul, 14, 2026

20,279 people reported to have side effects when taking Vimpat.
Among them, 24 people (0.12%) have Hyperkeratosis.

Among these 24 people:

How long have people been on Vimpat when they have Hyperkeratosis? *

What is the gender of people who have Hyperkeratosis when taking Vimpat? *

female: 33.33 %
male: 66.67 %

What is the age of people who have Hyperkeratosis when taking Vimpat? *

What are other drugs people take besides Vimpat? *

What are other side effects people have besides Hyperkeratosis? *

Cough: 17 people, 70.83%
Weakness: 16 people, 66.67%
Fatigue (feeling of tiredness): 16 people, 66.67%
Peripheral Nerve Lesion: 15 people, 62.50%
Dermal Cyst: 15 people, 62.50%
Peripheral Sensory Neuropathy (damage to one or more of your peripheral nerves): 15 people, 62.50%
Peripheral Motor Neuropathy (muscles in the body become progressively weaker over months to years): 15 people, 62.50%
Conjunctivitis (pink eye): 15 people, 62.50%
Pain In Extremity: 15 people, 62.50%
Mucosal Dryness (dryness of mucous membrane): 15 people, 62.50%

What are the existing conditions these people have? *

Brain Oedema (excess accumulation of fluid in the intracellular or extracellular spaces of the brain): 15 people, 62.50%
Metastases To Central Nervous System (cancer spreads to central nervous system): 15 people, 62.50%
High Blood Pressure: 15 people, 62.50%
Procedural Vomiting: 15 people, 62.50%
Procedural Nausea: 15 people, 62.50%
Procedural Headache: 15 people, 62.50%
Vision Blurred: 15 people, 62.50%
Pain: 15 people, 62.50%
Metastatic Malignant Melanoma (spreadable cancer tumour of melanine): 15 people, 62.50%
Malignant Melanoma (skin cancer rises from melancytes): 14 people, 58.33%

* Approximation only. Some reports may have incomplete information.

Do you take Vimpat and have Hyperkeratosis?

- Check whether Hyperkeratosis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Vimpat:

Vimpat (20,831 reports)

Hyperkeratosis treatments and more:

Hyperkeratosis (8,056 reports)

Browse all side effects of Vimpat:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hyperkeratosis:

Hyperkeratosis (780 drugs)

Browse all the conditions that are associated with Hyperkeratosis:

Hyperkeratosis (771 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on lacosamide (the active ingredients of Vimpat) and Vimpat (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.