Vimpat and Icterus - a phase IV clinical study of FDA data

Summary:

Icterus is reported as a side effect among people who take Vimpat (lacosamide), especially for people who are male, 40-49 old, have been taking the drug for 6 - 12 months also take Midazolam, and have Encephalitis autoimmune.

The phase IV clinical study analyzes which people have Icterus when taking Vimpat. It is created by eHealthMe based on reports of 20,279 people who have side effects when taking Vimpat from the FDA, and is updated regularly.

What is Vimpat?

Vimpat has active ingredients of lacosamide. It is often used in epilepsy. eHealthMe is studying from 20,831 Vimpat users. Check the latest studies of Vimpat.

What is Icterus?

Icterus (yellowish pigmentation of the skin) is found to be associated with 2,080 drugs and 3,015 conditions by eHealthMe. Check the latest studies of Icterus.

On Apr, 07, 2026

20,279 people reported to have side effects when taking Vimpat.
Among them, 14 people (0.07%) have Icterus.

Among these 14 people:

How long have people been on Vimpat when they have Icterus? *

What is the gender of people who have Icterus when taking Vimpat? *

female: 21.43 %
male: 78.57 %

What is the age of people who have Icterus when taking Vimpat? *

What are other drugs people take besides Vimpat? *

What are other side effects people have besides Icterus? *

Cholestasis (a condition where bile cannot flow from the liver to the duodenum): 5 people, 35.71%
Hepatocellular Injury (liver injury): 4 people, 28.57%
Hepatic Enzyme Increased: 4 people, 28.57%
Hyperbilirubinaemia (excess of bilirubin in the blood): 2 people, 14.29%
Blood Alkaline Phosphatase Increased: 2 people, 14.29%
Dyskinesia (abnormality or impairment of voluntary movement): 2 people, 14.29%
Nervous System Disorder (a general class of medical conditions affecting the nervous system): 1 person, 7.14%
Heart Sounds Abnormal: 1 person, 7.14%
Ascites (accumulation of fluid in the abdominal cavity): 1 person, 7.14%
Death: 1 person, 7.14%

What are the existing conditions these people have? *

Status Epilepticus (a life-threatening condition in which the brain is in a state of persistent seizure): 3 people, 21.43%
Encephalitis Autoimmune (autoimmune origin disturbances of consciousness and pyramidal signs, inflammation of the brain): 3 people, 21.43%
Short-Bowel Syndrome (a condition in which the body cannot absorb enough fluids and nutrients because part of the small intestine is missing): 2 people, 14.29%
Infection: 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Vimpat and have Icterus?

- Check whether Icterus is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Vimpat:

Vimpat (20,831 reports)

Icterus treatments and more:

Icterus (33,621 reports)

Browse all side effects of Vimpat:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Icterus:

Icterus (2,080 drugs)

Browse all the conditions that are associated with Icterus:

Icterus (3,015 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on lacosamide (the active ingredients of Vimpat) and Vimpat (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.