Vimpat and Obs - a phase IV clinical study of FDA data

Summary:

Obs is reported as a side effect among people who take Vimpat (lacosamide), especially for people who are male, 40-49 old, have been taking the drug for 2 - 5 years also take Keppra, and have Chronic lymphocytic leukaemia.

The phase IV clinical study analyzes which people have Obs when taking Vimpat. It is created by eHealthMe based on reports of 20,279 people who have side effects when taking Vimpat from the FDA, and is updated regularly.

What is Vimpat?

Vimpat has active ingredients of lacosamide. It is often used in epilepsy. eHealthMe is studying from 20,831 Vimpat users. Check the latest studies of Vimpat.

What is Obs?

Obs is found to be associated with 36 drugs and 226 conditions by eHealthMe. Check the latest studies of Obs.

On Apr, 27, 2026

20,279 people reported to have side effects when taking Vimpat.
Among them, 16 people (0.08%) have Obs.

Among these 16 people:

How long have people been on Vimpat when they have Obs? *

What is the gender of people who have Obs when taking Vimpat? *

female: 12.5 %
male: 87.5 %

What is the age of people who have Obs when taking Vimpat? *

What are other drugs people take besides Vimpat? *

What are other side effects people have besides Obs? *

Pain: 14 people, 87.50%
Oedema Peripheral (superficial swelling): 13 people, 81.25%
Belching (release of gas from the digestive tract): 13 people, 81.25%
Depression: 13 people, 81.25%
Dehydration (dryness resulting from the removal of water): 13 people, 81.25%
Muscle Twitching: 13 people, 81.25%
Common Peroneal Nerve Dysfunction (dysfunction of nerve controlling movement and sensation to the lower leg, foot and toes): 13 people, 81.25%
Dry Mouth: 13 people, 81.25%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 13 people, 81.25%
Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters): 13 people, 81.25%

What are the existing conditions these people have? *

Immunoglobulins Decreased: 13 people, 81.25%
Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 13 people, 81.25%
Drug-Induced Liver Injury (diseases of the liver that are caused by physician-prescribed medications): 8 people, 50.00%
Swelling Face: 1 person, 6.25%
Psoriasis (immune-mediated disease that affects the skin): 1 person, 6.25%
Pain: 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Vimpat and have Obs?

- Check whether Obs is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Vimpat:

Vimpat (20,831 reports)

Obs treatments and more:

Obs (298 reports)

Browse all side effects of Vimpat:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Obs:

Obs (36 drugs)

Browse all the conditions that are associated with Obs:

Obs (226 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on lacosamide (the active ingredients of Vimpat) and Vimpat (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.