Vioxx and Primary intestinal pseudo-obstruction - a phase IV clinical study of FDA data

Summary:

Primary intestinal pseudo-obstruction is reported as a side effect among people who take Vioxx (rofecoxib), especially for people who are male, 60+ old, have been taking the drug for 1 - 6 months also take Darvocet-N 100, and have Back pain.

The phase IV clinical study analyzes which people have Primary intestinal pseudo-obstruction when taking Vioxx. It is created by eHealthMe based on reports of 110,097 people who have side effects when taking Vioxx from the FDA, and is updated regularly.

What is Vioxx?

Vioxx has active ingredients of rofecoxib. It is often used in arthritis. eHealthMe is studying from 110,130 Vioxx users. Check the latest studies of Vioxx.

What is Primary intestinal pseudo-obstruction?

Primary intestinal pseudo-obstruction (symptoms of intestinal blockage without any physical signs of a blockage) is found to be associated with 100 drugs and 563 conditions by eHealthMe. Check the latest studies of Primary intestinal pseudo-obstruction.

On Jul, 08, 2026

110,097 people reported to have side effects when taking Vioxx.
Among them, 11 people (0.01%) have Primary intestinal pseudo-obstruction.

Could Vioxx cause Primary intestinal pseudo-obstruction?

Among these 11 people:

How long have people been on Vioxx when they have Primary intestinal pseudo-obstruction? *

What is the gender of people who have Primary intestinal pseudo-obstruction when taking Vioxx? *

female: 36.36 %
male: 63.64 %

What is the age of people who have Primary intestinal pseudo-obstruction when taking Vioxx? *

What are other drugs people take besides Vioxx? *

What are other side effects people have besides Primary intestinal pseudo-obstruction? *

High Blood Cholesterol: 10 people, 90.91%
Ventricular Tachycardia (rapid heartbeat that originates in one of the lower chambers (the ventricles) of the heart): 6 people, 54.55%
Ischaemic Cardiomyopathy (weakness in the muscle of the heart due to inadequate oxygen delivery to the myocardium with coronary artery disease): 6 people, 54.55%
Heart Attack: 6 people, 54.55%
Cardiac Failure Congestive: 6 people, 54.55%
Cardiac Aneurysm (a condition that can occur after a myocardial infarction due to the inadequate resistance of the new scar tissue to the systolic pressure): 6 people, 54.55%
Pharyngitis (inflammation of the pharynx, causing a sore throat): 5 people, 45.45%
High Blood Pressure: 5 people, 45.45%
Adverse Event: 5 people, 45.45%
Intestinal Obstruction: 5 people, 45.45%

What are the existing conditions these people have? *

Back Pain: 5 people, 45.45%
Osteoporosis (bones weak and more likely to break): 4 people, 36.36%
Thyroid Diseases: 2 people, 18.18%
Polymyalgia Rheumatica (pain in many muscles): 2 people, 18.18%
Joint Pain: 2 people, 18.18%
High Blood Cholesterol: 2 people, 18.18%

* Approximation only. Some reports may have incomplete information.

Do you take Vioxx and have Primary intestinal pseudo-obstruction?

- Check whether Primary intestinal pseudo-obstruction is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Vioxx:

Vioxx (110,130 reports)

Browse all side effects of Vioxx:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Primary intestinal pseudo-obstruction:

Primary intestinal pseudo-obstruction (100 drugs)

Browse all the conditions that are associated with Primary intestinal pseudo-obstruction:

Primary intestinal pseudo-obstruction (563 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on rofecoxib (the active ingredients of Vioxx) and Vioxx (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.