Vistaril and Nephropathy - a phase IV clinical study of FDA data

Summary:

Nephropathy is reported as a side effect among people who take Vistaril (hydroxyzine hydrochloride), especially for people who are female, 60+ old, also take Prilosec, and have Gastroesophageal reflux disease.

The phase IV clinical study analyzes which people have Nephropathy when taking Vistaril. It is created by eHealthMe based on reports of 8,641 people who have side effects when taking Vistaril from the FDA, and is updated regularly.

What is Vistaril?

Vistaril has active ingredients of hydroxyzine hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 9,565 Vistaril users. Check the latest studies of Vistaril.

What is Nephropathy?

Nephropathy (damage to or disease of a kidney) is found to be associated with 899 drugs and 734 conditions by eHealthMe. Check the latest studies of Nephropathy.



On Jul, 20, 2026

8,641 people reported to have side effects when taking Vistaril.
Among them, 21 people (0.24%) have Nephropathy.

Could Vistaril cause Nephropathy?

Among these 21 people:

What is the gender of people who have Nephropathy when taking Vistaril? *

  • female: 89.47 %
  • male: 10.53 %

What is the age of people who have Nephropathy when taking Vistaril? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 22.22 %
  • 40-49: 0.0 %
  • 50-59: 16.67 %
  • 60+: 61.11 %

What are other drugs people take besides Vistaril? *

  1. Prilosec: 14 people, 66.67%
  2. Prevacid: 13 people, 61.90%
  3. Ambien: 12 people, 57.14%
  4. Protonix: 11 people, 52.38%
  5. Zolpidem: 10 people, 47.62%
  6. Lipitor: 8 people, 38.10%
  7. Zoloft: 8 people, 38.10%
  8. Zetia: 8 people, 38.10%
  9. Prilosec Otc: 8 people, 38.10%
  10. Oxycodone: 7 people, 33.33%

What are other side effects people have besides Nephropathy? *

  1. Acute Kidney Failure: 14 people, 66.67%
  2. Chronic Kidney Disease: 12 people, 57.14%
  3. Interstitial Nephritis (inflammation of the kidney): 9 people, 42.86%
  4. Renal Impairment (severely reduced kidney function): 7 people, 33.33%
  5. Sepsis (a severe blood infection that can lead to organ failure and death): 5 people, 23.81%
  6. Multiple Myeloma (cancer of the plasma cells): 5 people, 23.81%
  7. Pneumonia Aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree): 5 people, 23.81%
  8. Nausea (feeling of having an urge to vomit): 4 people, 19.05%
  9. Renal Injury (kidney injury): 4 people, 19.05%
  10. Fatigue (feeling of tiredness): 4 people, 19.05%

What are the existing conditions these people have? *

  1. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 12 people, 57.14%
  2. Hypersensitivity: 10 people, 47.62%
  3. Depression: 8 people, 38.10%
  4. High Blood Cholesterol: 8 people, 38.10%
  5. Seizures (abnormal excessive or synchronous neuronal activity in the brain): 7 people, 33.33%
  6. Nasal Dryness (dry nose): 7 people, 33.33%
  7. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 6 people, 28.57%
  8. Pain: 6 people, 28.57%
  9. High Blood Pressure: 6 people, 28.57%
  10. Stable Angina (a constant chest pain): 5 people, 23.81%

* Approximation only. Some reports may have incomplete information.

Do you take Vistaril and have Nephropathy?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Vistaril:

Nephropathy treatments and more:

How severe was Nephropathy and when was it recovered:

Expand to all the drugs that have ingredients of hydroxyzine hydrochloride:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Vistaril:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Nephropathy:

Browse all the conditions that are associated with Nephropathy:

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on hydroxyzine hydrochloride (the active ingredients of Vistaril) and Vistaril (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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