Vistaril and Neurotoxicity - a phase IV clinical study of FDA data

Summary:

Neurotoxicity is reported as a side effect among people who take Vistaril (hydroxyzine hydrochloride), especially for people who are female, 10-19 old, have been taking the drug for 1 - 6 months also take Benadryl, and have Acute lymphocytic leukemia (all).

The phase IV clinical study analyzes which people have Neurotoxicity when taking Vistaril. It is created by eHealthMe based on reports of 8,641 people who have side effects when taking Vistaril from the FDA, and is updated regularly.

What is Vistaril?

Vistaril has active ingredients of hydroxyzine hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 9,565 Vistaril users. Check the latest studies of Vistaril.

What is Neurotoxicity?

Neurotoxicity (when the exposure to natural or artificial toxic substances, which are called neurotoxins, alters the normal activity of the nervous system) is found to be associated with 684 drugs and 846 conditions by eHealthMe. Check the latest studies of Neurotoxicity.

On Jul, 04, 2026

8,641 people reported to have side effects when taking Vistaril.
Among them, 12 people (0.14%) have Neurotoxicity.

Among these 12 people:

How long have people been on Vistaril when they have Neurotoxicity? *

What is the gender of people who have Neurotoxicity when taking Vistaril? *

female: 58.33 %
male: 41.67 %

What is the age of people who have Neurotoxicity when taking Vistaril? *

What are other drugs people take besides Vistaril? *

What are other side effects people have besides Neurotoxicity? *

Agitation (state of anxiety or nervous excitement): 8 people, 66.67%
Hyperglycemia (high blood sugar): 6 people, 50.00%
Gallbladder Enlargement: 5 people, 41.67%
Fluid Overload (too much fluid in the blood): 5 people, 41.67%
Iron Overload: 5 people, 41.67%
Hyperbilirubinaemia (excess of bilirubin in the blood): 5 people, 41.67%
Hepatomegaly (abnormal enlargement of the liver): 5 people, 41.67%
Hepatic Failure (liver failure): 5 people, 41.67%
Hepatic Cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue): 5 people, 41.67%
Headache (pain in head): 5 people, 41.67%

What are the existing conditions these people have? *

Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 5 people, 41.67%
Lung Cancer Stage Unspecified (Excl Metastatic Tumors To Lung): 2 people, 16.67%
Subdiaphragmatic Abscess: 1 person, 8.33%
Sedation: 1 person, 8.33%
Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 1 person, 8.33%
Lung Neoplasm Malignant (cancer tumour of lung): 1 person, 8.33%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Vistaril and have Neurotoxicity?

- Check whether Neurotoxicity is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Vistaril:

Vistaril (9,565 reports)

Neurotoxicity treatments and more:

Neurotoxicity (16,742 reports)

Browse all side effects of Vistaril:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Neurotoxicity:

Neurotoxicity (684 drugs)

Browse all the conditions that are associated with Neurotoxicity:

Neurotoxicity (846 conditions)

Related publications that referenced our studies

Ate? ?, Arikan MF, Kaplan M, Altay M, "Hydroxyzine induced pancytopenia and petechial rashes: a rare complication", Journal Of Contemporary Medicine, 2017 Jan .
Ate? ?, Arikan MF, Kaplan M, Altay M, "Hydroxyzine induced pancytopenia and petechial rashes: a rare complication", Journal Of Contemporary Medicine, 2017 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on hydroxyzine hydrochloride (the active ingredients of Vistaril) and Vistaril (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.