Vistaril and Sciatica - a phase IV clinical study of FDA data

Summary:

Sciatica is reported as a side effect among people who take Vistaril (hydroxyzine hydrochloride), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Klonopin, and have Nausea.

The phase IV clinical study analyzes which people have Sciatica when taking Vistaril. It is created by eHealthMe based on reports of 8,641 people who have side effects when taking Vistaril from the FDA, and is updated regularly.

What is Vistaril?

Vistaril has active ingredients of hydroxyzine hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 9,565 Vistaril users. Check the latest studies of Vistaril.

What is Sciatica?

Sciatica (a set of symptoms including pain caused by general compression or irritation of one of five spinal nerve roots of each sciatic nerve) is found to be associated with 1,144 drugs and 1,428 conditions by eHealthMe. Check the latest studies of Sciatica.

On Apr, 10, 2026

8,641 people reported to have side effects when taking Vistaril.
Among them, 22 people (0.25%) have Sciatica.

Among these 22 people:

How long have people been on Vistaril when they have Sciatica? *

What is the gender of people who have Sciatica when taking Vistaril? *

female: 90.48 %
male: 9.52 %

What is the age of people who have Sciatica when taking Vistaril? *

What are other drugs people take besides Vistaril? *

What are other side effects people have besides Sciatica? *

Back Pain: 15 people, 68.18%
Fall: 13 people, 59.09%
Weakness: 11 people, 50.00%
Cough: 11 people, 50.00%
Hoarseness Or Changing Voice: 10 people, 45.45%
Joint Pain: 9 people, 40.91%
Hyperhidrosis (abnormally increased sweating): 9 people, 40.91%
Dyspnea (difficult or laboured breathing): 9 people, 40.91%
High Blood Cholesterol: 9 people, 40.91%
Nausea (feeling of having an urge to vomit): 9 people, 40.91%

What are the existing conditions these people have? *

Pain: 8 people, 36.36%
Nausea And Vomiting: 8 people, 36.36%
Nausea (feeling of having an urge to vomit): 8 people, 36.36%
Bipolar Disorder (mood disorder): 5 people, 22.73%
Bipolar I Disorder (mood disorder that is characterized by at least one manic or mixed episode): 5 people, 22.73%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 5 people, 22.73%
Wheezing (a high-pitched whistling sound made while you breath): 4 people, 18.18%
Sleep Disorder: 4 people, 18.18%
Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 4 people, 18.18%
Cough: 4 people, 18.18%

* Approximation only. Some reports may have incomplete information.

Do you take Vistaril and have Sciatica?

- Check whether Sciatica is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Vistaril:

Vistaril (9,565 reports)

Sciatica treatments and more:

Sciatica (28,509 reports)

Browse all side effects of Vistaril:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Sciatica:

Sciatica (1,144 drugs)

Browse all the conditions that are associated with Sciatica:

Sciatica (1,428 conditions)

Related publications that referenced our studies

Ate? ?, Arikan MF, Kaplan M, Altay M, "Hydroxyzine induced pancytopenia and petechial rashes: a rare complication", Journal Of Contemporary Medicine, 2017 Jan .
Ate? ?, Arikan MF, Kaplan M, Altay M, "Hydroxyzine induced pancytopenia and petechial rashes: a rare complication", Journal Of Contemporary Medicine, 2017 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on hydroxyzine hydrochloride (the active ingredients of Vistaril) and Vistaril (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.