Vitamin b6 and Red cell distribution width increased - a phase IV clinical study of FDA data

Summary:

Red cell distribution width increased is reported as a side effect among people who take Vitamin b6 (pyridoxine), especially for people who are female, 60+ old, also take Amlodipine, and have Breast cancer.

The phase IV clinical study analyzes which people have Red cell distribution width increased when taking Vitamin b6. It is created by eHealthMe based on reports of 15,719 people who have side effects when taking Vitamin b6 from the FDA, and is updated regularly.

What is Vitamin b6?

Vitamin b6 has active ingredients of pyridoxine. It is often used in stress and anxiety. eHealthMe is studying from 16,183 Vitamin b6 users. Check the latest studies of Vitamin b6.

What is Red cell distribution width increased?

Red cell distribution width increased is found to be associated with 604 drugs and 656 conditions by eHealthMe. Check the latest studies of Red cell distribution width increased.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 25, 2026

15,719 people reported to have side effects when taking Vitamin b6.
Among them, 11 people (0.07%) have Red cell distribution width increased.

Could Vitamin b6 cause Red cell distribution width increased?

Among these 11 people:

What is the gender of people who have Red cell distribution width increased when taking Vitamin b6? *

female: 77.78 %
male: 22.22 %

What is the age of people who have Red cell distribution width increased when taking Vitamin b6? *

What are other drugs people take besides Vitamin b6? *

What are other side effects people have besides Red cell distribution width increased? *

Lymphocyte Count Decreased: 8 people, 72.73%
Haematocrit Decreased: 6 people, 54.55%
Red Blood Cell Count Decreased: 5 people, 45.45%
Haemoglobin Decreased: 5 people, 45.45%
Neutrophil Count Increased (excess than normal number of neutrophil a type of blood cell): 4 people, 36.36%
Thrombocytopenia (decrease of platelets in blood): 4 people, 36.36%
Joint Pain: 3 people, 27.27%
Back Pain: 3 people, 27.27%
White Blood Cell Count Decreased: 3 people, 27.27%
Hyperkalemia (damage to or disease of the kidney): 3 people, 27.27%

What are the existing conditions these people have? *

Polycythaemia Vera (blood disorder in which the bone marrow makes too many red blood cells): 2 people, 18.18%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 18.18%
High Blood Pressure: 2 people, 18.18%
Facial Paralysis (loss of function of face muscle): 2 people, 18.18%
Essential Thrombocythaemia (chronic blood cancer): 2 people, 18.18%
Cough: 2 people, 18.18%
Breast Cancer Metastatic: 2 people, 18.18%
Breast Cancer: 2 people, 18.18%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 1 person, 9.09%
Peripheral Neuropathy (damage to nerves of the peripheral nervous system): 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Vitamin b6 and have Red cell distribution width increased?

- Check whether Red cell distribution width increased is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Vitamin b6:

Vitamin b6 (16,183 reports)

Browse all side effects of Vitamin b6:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Red cell distribution width increased:

Red cell distribution width increased (604 drugs)

Browse all the conditions that are associated with Red cell distribution width increased:

Red cell distribution width increased (656 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on pyridoxine (the active ingredients of Vitamin b6) and Vitamin b6 (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.