Vitamin d and Mitral valve prolapse - a phase IV clinical study of FDA data

Summary:

Mitral valve prolapse is reported as a side effect among people who take Vitamin d (ergocalciferol), especially for people who are female, 60+ old, have been taking the drug for 10+ years also take Xyrem, and have Narcolepsy.

The phase IV clinical study analyzes which people have Mitral valve prolapse when taking Vitamin d. It is created by eHealthMe based on reports of 282,675 people who have side effects when taking Vitamin d from the FDA, and is updated regularly.

What is Vitamin d?

Vitamin d has active ingredients of ergocalciferol. It is often used in low vitamin d. eHealthMe is studying from 294,095 Vitamin d users. Check the latest studies of Vitamin d.

What is Mitral valve prolapse?

Mitral valve prolapse (heart's mitral valve doesn't work well) is found to be associated with 504 drugs and 859 conditions by eHealthMe. Check the latest studies of Mitral valve prolapse.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Jul, 06, 2026

282,675 people reported to have side effects when taking Vitamin d.
Among them, 55 people (0.02%) have Mitral valve prolapse.

Could Vitamin d cause Mitral valve prolapse?

Among these 55 people:

How long have people been on Vitamin d when they have Mitral valve prolapse? *

What is the gender of people who have Mitral valve prolapse when taking Vitamin d? *

female: 94.34 %
male: 5.66 %

What is the age of people who have Mitral valve prolapse when taking Vitamin d? *

What are other drugs people take besides Vitamin d? *

What are other side effects people have besides Mitral valve prolapse? *

Osteoarthritis (a joint disease caused by cartilage loss in a joint): 20 people, 36.36%
High Blood Pressure: 16 people, 29.09%
Pain In Extremity: 13 people, 23.64%
Femur Fracture: 13 people, 23.64%
Joint Pain: 13 people, 23.64%
Neuropathy Peripheral (surface nerve damage): 12 people, 21.82%
Depression: 11 people, 20.00%
Fall: 10 people, 18.18%
Back Pain: 9 people, 16.36%
Dyspnea (difficult or laboured breathing): 9 people, 16.36%

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 17 people, 30.91%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 15 people, 27.27%
High Blood Pressure: 8 people, 14.55%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 8 people, 14.55%
Drowsiness: 7 people, 12.73%
Pain: 7 people, 12.73%
Insomnia (sleeplessness): 5 people, 9.09%
Osteopenia (a condition where bone mineral density is lower than normal): 4 people, 7.27%
Cardiac Disorder: 3 people, 5.45%
Herpes Virus Infection: 3 people, 5.45%

* Approximation only. Some reports may have incomplete information.

Do you take Vitamin d and have Mitral valve prolapse?

- Check whether Mitral valve prolapse is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Vitamin d:

Vitamin d (294,095 reports)

Browse all side effects of Vitamin d:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Mitral valve prolapse:

Mitral valve prolapse (504 drugs)

Browse all the conditions that are associated with Mitral valve prolapse:

Mitral valve prolapse (859 conditions)

Related publications that referenced our studies

Kapoor S, "Influence of Vitamin D Consumption and Levels on the Development of Psychiatric Disorders", Lee, Y. J., & Park, K. (2018). Secondary Raynaud’s Phenomenon and Skin Necrosis of Toes in the Paraplegic Patient with Hypertension.?Drug safety-case reports,?5(1), 7., 2014 Aug .
Kapoor S, "Influence of Vitamin D Consumption and Levels on the Development of Psychiatric Disorders", Lee, Y. J., & Park, K. (2018). Secondary Raynaud’s Phenomenon and Skin Necrosis of Toes in the Paraplegic Patient with Hypertension.?Drug safety-case reports,?5(1), 7., 2014 Aug .

How the study uses the data?

The study uses data from the FDA. It is based on ergocalciferol (the active ingredients of Vitamin d) and Vitamin d (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.