Vitamin k1 and Rales - a phase IV clinical study of FDA data

Summary:

Rales is reported as a side effect among people who take Vitamin k1 (phytonadione), especially for people who are male, 60+ old, also take Albuterol, and have Dyspnea.

The phase IV clinical study analyzes which people have Rales when taking Vitamin k1. It is created by eHealthMe based on reports of 939 people who have side effects when taking Vitamin k1 from the FDA, and is updated regularly.

What is Vitamin k1?

Vitamin k1 has active ingredients of phytonadione. eHealthMe is studying from 964 Vitamin k1 users. Check the latest studies of Vitamin k1.

What is Rales?

Rales (an abnormal respiratory sound characterized by fine crackles) is found to be associated with 899 drugs and 946 conditions by eHealthMe. Check the latest studies of Rales.



On Jul, 14, 2026

939 people reported to have side effects when taking Vitamin k1.
Among them, 15 people (1.6%) have Rales.

Could Vitamin k1 cause Rales?

Among these 15 people:

What is the gender of people who have Rales when taking Vitamin k1? *

  • female: 0.0 %
  • male: 100 %

What is the age of people who have Rales when taking Vitamin k1? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 0.0 %
  • 60+: 100 %

What are other drugs people take besides Vitamin k1? *

  1. Phytonadione: 15 people, 100.00%
  2. Albuterol: 15 people, 100.00%
  3. Budesonide: 14 people, 93.33%
  4. Nitroglycerin: 14 people, 93.33%
  5. Efinaconazole: 14 people, 93.33%
  6. Metronidazole: 12 people, 80.00%
  7. Ipratropium Bromide: 9 people, 60.00%
  8. Polyethylene Glycol 3350: 7 people, 46.67%
  9. Aranesp: 6 people, 40.00%
  10. Gabapentin: 6 people, 40.00%

What are other side effects people have besides Rales? *

  1. Wheezing (a high-pitched whistling sound made while you breath): 15 people, 100.00%
  2. Coughing Up Blood: 15 people, 100.00%
  3. Hyponatremia (abnormally low level of sodium in the blood; associated with dehydration): 15 people, 100.00%
  4. High Blood Cholesterol: 15 people, 100.00%
  5. Headache (pain in head): 15 people, 100.00%
  6. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 15 people, 100.00%
  7. Fever: 15 people, 100.00%
  8. Fatigue (feeling of tiredness): 15 people, 100.00%
  9. Dyspnea (difficult or laboured breathing): 15 people, 100.00%
  10. Dry Mouth: 15 people, 100.00%

What are the existing conditions these people have? *

  1. Sleep Disorder: 15 people, 100.00%
  2. Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 15 people, 100.00%
  3. Dyspnea (difficult or laboured breathing): 15 people, 100.00%
  4. Bacterial Infection: 12 people, 80.00%
  5. Constipation: 11 people, 73.33%
  6. Swelling: 7 people, 46.67%
  7. Ventricular Fibrillation (abnormally irregular heart rhythm): 6 people, 40.00%
  8. High Blood Cholesterol: 6 people, 40.00%
  9. Blood Phosphorus Increased: 6 people, 40.00%
  10. Blood Uric Acid Increased: 6 people, 40.00%

* Approximation only. Some reports may have incomplete information.

Do you take Vitamin k1 and have Rales?

- Check whether Rales is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Vitamin k1:

Rales treatments and more:

How severe was Rales and when was it recovered:

Expand to all the drugs that have ingredients of phytonadione:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Vitamin k1:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Rales:

Browse all the conditions that are associated with Rales:


How the study uses the data?

The study uses data from the FDA. It is based on phytonadione (the active ingredients of Vitamin k1) and Vitamin k1 (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: