Vitamins and Bicuspid aortic valve - a phase IV clinical study of FDA data

Summary:

Bicuspid aortic valve is reported as a side effect among people who take Vitamins (ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e), especially for people who are male, 0-1 old, have been taking the drug for 1 - 2 years also take Zoloft, and have Depression.

The phase IV clinical study analyzes which people have Bicuspid aortic valve when taking Vitamins. It is created by eHealthMe based on reports of 121,858 people who have side effects when taking Vitamins from the FDA, and is updated regularly.

What is Vitamins?

Vitamins has active ingredients of ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e. It is often used in vitamin supplementation. eHealthMe is studying from 122,457 Vitamins users. Check the latest studies of Vitamins.

What is Bicuspid aortic valve?

Bicuspid aortic valve is found to be associated with 60 drugs and 75 conditions by eHealthMe. Check the latest studies of Bicuspid aortic valve.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 22, 2026

121,858 people reported to have side effects when taking Vitamins.
Among them, 94 people (0.08%) have Bicuspid aortic valve.

Could Vitamins cause Bicuspid aortic valve?

Among these 94 people:

How long have people been on Vitamins when they have Bicuspid aortic valve? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 100 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Bicuspid aortic valve when taking Vitamins? *

  • female: 38.46 %
  • male: 61.54 %

What is the age of people who have Bicuspid aortic valve when taking Vitamins? *

  • 0-1: 28.57 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 4.76 %
  • 40-49: 9.52 %
  • 50-59: 14.29 %
  • 60+: 14.29 %

What are other drugs people take besides Vitamins? *

  1. Zoloft: 42 people, 44.68%
  2. Paxil: 39 people, 41.49%
  3. Tylenol: 8 people, 8.51%
  4. Flexeril: 7 people, 7.45%
  5. Paxil Cr: 7 people, 7.45%
  6. Effexor: 7 people, 7.45%
  7. Zofran: 6 people, 6.38%
  8. Effexor Xr: 5 people, 5.32%
  9. Ibuprofen: 5 people, 5.32%
  10. Benadryl: 5 people, 5.32%

What are other side effects people have besides Bicuspid aortic valve? *

  1. Coarctation Of The Aorta (narrowing of the part of aorta): 51 people, 54.26%
  2. Drug Exposure During Pregnancy: 30 people, 31.91%
  3. Foetal Exposure During Pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect): 20 people, 21.28%
  4. Maternal Exposure During Pregnancy (use of substance during pregnancy): 19 people, 20.21%
  5. Tricuspid Valve Incompetence (inefficient heart valve): 18 people, 19.15%
  6. Aortic Stenosis (obstruction to the outflow of blood from the left ventricle into the aorta): 17 people, 18.09%
  7. Aortic Dilatation: 12 people, 12.77%
  8. Dilatation Ventricular: 11 people, 11.70%
  9. Enlarged Heart: 11 people, 11.70%
  10. Ventricular Hypertrophy (enlargement of ventricles (lower chambers) in the heart): 9 people, 9.57%

What are the existing conditions these people have? *

  1. Depression: 51 people, 54.26%
  2. Stress And Anxiety: 21 people, 22.34%
  3. Nausea (feeling of having an urge to vomit): 5 people, 5.32%
  4. Postpartum Depression (depression suffered by a mother following childbirth): 5 people, 5.32%
  5. High Blood Pressure: 4 people, 4.26%
  6. Nausea And Vomiting: 4 people, 4.26%
  7. Urinary Tract Infection: 3 people, 3.19%
  8. Dyspnea (difficult or laboured breathing): 3 people, 3.19%
  9. Nasal Congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels): 3 people, 3.19%
  10. Bipolar Disorder (mood disorder): 3 people, 3.19%

* Approximation only. Some reports may have incomplete information.

Do you take Vitamins and have Bicuspid aortic valve?

- Check whether Bicuspid aortic valve is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Vitamins:

Bicuspid aortic valve treatments and more:

How severe was Bicuspid aortic valve and when was it recovered:

Expand to all the drugs that have ingredients of ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Vitamins:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Bicuspid aortic valve:

Browse all the conditions that are associated with Bicuspid aortic valve:


How the study uses the data?

The study uses data from the FDA. It is based on ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e (the active ingredients of Vitamins) and Vitamins (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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