Vitamins and Periventricular leukomalacia - a phase IV clinical study of FDA data

Summary:

Periventricular leukomalacia is reported as a side effect among people who take Vitamins (ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e), especially for people who are male, 20-29 old, have been taking the drug for 6 - 12 months also take Protonix, and have Foetal exposure during pregnancy.

The phase IV clinical study analyzes which people have Periventricular leukomalacia when taking Vitamins. It is created by eHealthMe based on reports of 121,858 people who have side effects when taking Vitamins from the FDA, and is updated regularly.

What is Vitamins?

Vitamins has active ingredients of ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e. It is often used in vitamin supplementation. eHealthMe is studying from 122,456 Vitamins users. Check the latest studies of Vitamins.

What is Periventricular leukomalacia?

Periventricular leukomalacia (white-matter brain injury) is found to be associated with 47 drugs and 160 conditions by eHealthMe. Check the latest studies of Periventricular leukomalacia.



On Jul, 17, 2026

121,858 people reported to have side effects when taking Vitamins.
Among them, 12 people (0.01%) have Periventricular leukomalacia.

Could Vitamins cause Periventricular leukomalacia?

Among these 12 people:

How long have people been on Vitamins when they have Periventricular leukomalacia? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 50 %
  • 6 - 12 months: 50 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Periventricular leukomalacia when taking Vitamins? *

  • female: 25 %
  • male: 75 %

What is the age of people who have Periventricular leukomalacia when taking Vitamins? *

  • 0-1: 16.67 %
  • 2-9: 16.67 %
  • 10-19: 0.0 %
  • 20-29: 33.33 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 16.67 %
  • 60+: 0.0 %

What are other drugs people take besides Vitamins? *

  1. Zoloft: 3 people, 25.00%
  2. Protonix: 3 people, 25.00%
  3. Amoxicillin: 2 people, 16.67%
  4. Bentyl: 2 people, 16.67%
  5. Cymbalta: 2 people, 16.67%
  6. Famotidine: 2 people, 16.67%
  7. Zofran: 2 people, 16.67%
  8. Lortab: 2 people, 16.67%
  9. Miralax: 2 people, 16.67%
  10. Neurontin: 2 people, 16.67%

What are other side effects people have besides Periventricular leukomalacia? *

  1. Premature Baby: 7 people, 58.33%
  2. Weakness: 3 people, 25.00%
  3. Maternal Exposure During Pregnancy (use of substance during pregnancy): 3 people, 25.00%
  4. Developmental Delay: 3 people, 25.00%
  5. Encephalopathy (functioning of the brain is affected by some agent or condition): 3 people, 25.00%
  6. Cerebral Palsy: 3 people, 25.00%
  7. Emotional Distress: 2 people, 16.67%
  8. Ear Barotrauma (discomfort and possible damage in the ear due to pressure differences between the inside and outside of the eardrum): 2 people, 16.67%
  9. Drug Withdrawal Syndrome Neonatal (prenatal nas is caused by discontinuation of drugs taken by the pregnant mother): 2 people, 16.67%
  10. Intraventricular Haemorrhage (intraventricular bleeding): 2 people, 16.67%

What are the existing conditions these people have? *

  1. Foetal Exposure During Pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect): 4 people, 33.33%
  2. Depression: 2 people, 16.67%
  3. Stress And Anxiety: 1 person, 8.33%
  4. Premature Baby: 1 person, 8.33%
  5. Multiple Myeloma (cancer of the plasma cells): 1 person, 8.33%
  6. Low Birth Weight Baby: 1 person, 8.33%
  7. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 1 person, 8.33%
  8. Birth Control: 1 person, 8.33%
  9. Affective Disorder (mental disorder): 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Vitamins and have Periventricular leukomalacia?

- Check whether Periventricular leukomalacia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Vitamins:

Periventricular leukomalacia treatments and more:

How severe was Periventricular leukomalacia and when was it recovered:

Expand to all the drugs that have ingredients of ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Vitamins:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Periventricular leukomalacia:

Browse all the conditions that are associated with Periventricular leukomalacia:


How the study uses the data?

The study uses data from the FDA. It is based on ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e (the active ingredients of Vitamins) and Vitamins (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: