Vitrakvi and Nausea and vomiting - a phase IV clinical study of FDA data

Summary:

Nausea and vomiting is reported as a side effect among people who take Vitrakvi (larotrectinib), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Coumadin, and have Endocrine neoplasm.

The phase IV clinical study analyzes which people have Nausea and vomiting when taking Vitrakvi. It is created by eHealthMe based on reports of 594 people who have side effects when taking Vitrakvi from the FDA, and is updated regularly.

What is Vitrakvi?

Vitrakvi has active ingredients of larotrectinib. eHealthMe is studying from 594 Vitrakvi users. Check the latest studies of Vitrakvi.

What is Nausea and vomiting?

Nausea and vomiting is found to be associated with 3,712 drugs and 5,745 conditions by eHealthMe. Check the latest studies of Nausea and vomiting.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 11, 2026

594 people reported to have side effects when taking Vitrakvi.
Among them, 12 people (2.02%) have Nausea and vomiting.

Could Vitrakvi cause Nausea and vomiting?

Among these 12 people:

How long have people been on Vitrakvi when they have Nausea and vomiting? *

What is the gender of people who have Nausea and vomiting when taking Vitrakvi? *

female: 36.36 %
male: 63.64 %

What is the age of people who have Nausea and vomiting when taking Vitrakvi? *

What are other drugs people take besides Vitrakvi? *

Fragmin: 2 people, 16.67%
Coumadin: 2 people, 16.67%
Vitamin D3: 1 person, 8.33%
Synagis: 1 person, 8.33%
Ondansetron Hydrochloride: 1 person, 8.33%
Famotidine: 1 person, 8.33%
Clemastine Fumarate: 1 person, 8.33%
Acetaminophen: 1 person, 8.33%

What are other side effects people have besides Nausea and vomiting? *

Fatigue (feeling of tiredness): 4 people, 33.33%
Nausea (feeling of having an urge to vomit): 3 people, 25.00%
Weight Decreased: 2 people, 16.67%
Neuropathy Peripheral (surface nerve damage): 2 people, 16.67%
Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 2 people, 16.67%
Depressed Mood: 2 people, 16.67%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 16.67%
Memory Loss: 2 people, 16.67%
Abdominal Pain: 2 people, 16.67%
Pulmonary Thrombosis (scarring in the lungs): 2 people, 16.67%

What are the existing conditions these people have? *

Lung Cancer - Non-Small Cell (lung cancer): 2 people, 16.67%
Glioblastoma (most common and most aggressive malignant primary brain tumour in humans): 2 people, 16.67%
Endocrine Neoplasm (tumour of endocrine glands): 2 people, 16.67%
Rhabdomyosarcoma (cancer of the bone, soft tissues, or connective tissue (e.g., tendon or cartilage)): 1 person, 8.33%
Premature Baby: 1 person, 8.33%
Neoplasm Malignant (cancer tumour): 1 person, 8.33%
Lung Neoplasm Malignant (cancer tumour of lung): 1 person, 8.33%
Fibrosarcoma (cancerous tumour that originates in the connective tissue found at the ends of bones of the arm or legs): 1 person, 8.33%
Breast Cancer: 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Vitrakvi and have Nausea and vomiting?

- Check whether Nausea and vomiting is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Vitrakvi:

Vitrakvi (594 reports)

Browse all side effects of Vitrakvi:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Nausea and vomiting:

Nausea and vomiting (3,712 drugs)

Browse all the conditions that are associated with Nausea and vomiting:

Nausea and vomiting (5,745 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on larotrectinib (the active ingredients of Vitrakvi) and Vitrakvi (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.