Vivelle and Hypoglycemia - a phase IV clinical study of FDA data

Summary:

Hypoglycemia is reported as a side effect among people who take Vivelle (estradiol), especially for people who are female, 50-59 old, have been taking the drug for 1 - 6 months also take Estraderm, and have Osteoporosis.

The phase IV clinical study analyzes which people have Hypoglycemia when taking Vivelle. It is created by eHealthMe based on reports of 6,258 people who have side effects when taking Vivelle from the FDA, and is updated regularly.

What is Vivelle?

Vivelle has active ingredients of estradiol. It is often used in hormone replacement therapy. eHealthMe is studying from 6,624 Vivelle users. Check the latest studies of Vivelle.

What is Hypoglycemia?

Hypoglycemia (low blood sugar) is found to be associated with 1,703 drugs and 2,379 conditions by eHealthMe. Check the latest studies of Hypoglycemia.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 31, 2026

6,258 people reported to have side effects when taking Vivelle.
Among them, 12 people (0.19%) have Hypoglycemia.

Among these 12 people:

How long have people been on Vivelle when they have Hypoglycemia? *

What is the gender of people who have Hypoglycemia when taking Vivelle? *

female: 100 %
male: 0.0 %

What is the age of people who have Hypoglycemia when taking Vivelle? *

What are other drugs people take besides Vivelle? *

Estraderm: 6 people, 50.00%
Provera: 5 people, 41.67%
Premarin: 5 people, 41.67%
Fosamax: 3 people, 25.00%
Metformin: 2 people, 16.67%
Promethazine W/ Codeine: 2 people, 16.67%
Protonix: 2 people, 16.67%
Prilosec: 2 people, 16.67%
Reclast: 2 people, 16.67%
Rhinocort: 2 people, 16.67%

What are other side effects people have besides Hypoglycemia? *

Pain In Extremity: 8 people, 66.67%
Asthma: 7 people, 58.33%
Migraine (headache): 7 people, 58.33%
Memory Loss: 7 people, 58.33%
Depression: 7 people, 58.33%
Transient Ischaemic Attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow)): 6 people, 50.00%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 6 people, 50.00%
Neuropathy Peripheral (surface nerve damage): 6 people, 50.00%
Lymph Follicular Hypertrophy (an increase in the size of the lymph node follicles): 6 people, 50.00%
Stress And Anxiety: 6 people, 50.00%

What are the existing conditions these people have? *

Osteoporosis (bones weak and more likely to break): 3 people, 25.00%
Type 2 Diabetes: 2 people, 16.67%
Migraine (headache): 2 people, 16.67%
Insomnia (sleeplessness): 2 people, 16.67%
Cough: 2 people, 16.67%
Nausea And Vomiting: 1 person, 8.33%
Nausea (feeling of having an urge to vomit): 1 person, 8.33%
Lung Neoplasm Malignant (cancer tumour of lung): 1 person, 8.33%
Fibromyalgia (a long-term condition which causes pain all over the body): 1 person, 8.33%
Cervix Carcinoma (cancer of cervix): 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Vivelle and have Hypoglycemia?

- Check whether Hypoglycemia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Vivelle:

Vivelle (6,624 reports)

Hypoglycemia treatments and more:

Hypoglycemia (57,734 reports)

Browse all side effects of Vivelle:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hypoglycemia:

Hypoglycemia (1,703 drugs)

Browse all the conditions that are associated with Hypoglycemia:

Hypoglycemia (2,379 conditions)

Related publications that referenced our studies

Hipoglisemi RB, "Rasagiline-Induced Hypoglycemia", , 2016 Jan .
Hipoglisemi RB, "Rasagiline-Induced Hypoglycemia", , 2016 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on estradiol (the active ingredients of Vivelle) and Vivelle (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.