Vivelle and Hypotension aggravated - a phase IV clinical study of FDA data

Summary:

Hypotension aggravated is reported as a side effect among people who take Vivelle (estradiol), especially for people who are female, 50-59 old, have been taking the drug for 2 - 5 years also take Synthroid, and have Multiple sclerosis.

The phase IV clinical study analyzes which people have Hypotension aggravated when taking Vivelle. It is created by eHealthMe based on reports of 6,258 people who have side effects when taking Vivelle from the FDA, and is updated regularly.

What is Vivelle?

Vivelle has active ingredients of estradiol. It is often used in hormone replacement therapy. eHealthMe is studying from 6,624 Vivelle users. Check the latest studies of Vivelle.

What is Hypotension aggravated?

Hypotension aggravated (more troublesome low blood pressure) is found to be associated with 1,968 drugs and 748 conditions by eHealthMe. Check the latest studies of Hypotension aggravated.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 31, 2026

6,258 people reported to have side effects when taking Vivelle.
Among them, 82 people (1.31%) have Hypotension aggravated.

Could Vivelle cause Hypotension aggravated?

Among these 82 people:

How long have people been on Vivelle when they have Hypotension aggravated? *

What is the gender of people who have Hypotension aggravated when taking Vivelle? *

female: 96.3 %
male: 3.7 %

What is the age of people who have Hypotension aggravated when taking Vivelle? *

What are other drugs people take besides Vivelle? *

What are other side effects people have besides Hypotension aggravated? *

Dizziness: 40 people, 48.78%
Nausea (feeling of having an urge to vomit): 28 people, 34.15%
Fatigue (feeling of tiredness): 27 people, 32.93%
Weakness: 22 people, 26.83%
High Blood Pressure: 22 people, 26.83%
Dyspnea (difficult or laboured breathing): 22 people, 26.83%
Nausea And Vomiting: 21 people, 25.61%
Stress And Anxiety: 20 people, 24.39%
Chest Pain: 20 people, 24.39%
Feeling Abnormal: 20 people, 24.39%

What are the existing conditions these people have? *

Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 8 people, 9.76%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 6 people, 7.32%
High Blood Pressure: 6 people, 7.32%
Gait Disturbance: 5 people, 6.10%
Menopause (end of monthly cycles in women): 5 people, 6.10%
Fibromyalgia (a long-term condition which causes pain all over the body): 4 people, 4.88%
Multiple Myeloma (cancer of the plasma cells): 4 people, 4.88%
Restless Leg Syndrome (a powerful urge to move your legs): 3 people, 3.66%
Night Sweats (sweating in night): 3 people, 3.66%
Stress And Anxiety: 3 people, 3.66%

* Approximation only. Some reports may have incomplete information.

Do you take Vivelle and have Hypotension aggravated?

- Check whether Hypotension aggravated is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Vivelle:

Vivelle (6,624 reports)

Browse all side effects of Vivelle:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hypotension aggravated:

Hypotension aggravated (1,969 drugs)

Browse all the conditions that are associated with Hypotension aggravated:

Hypotension aggravated (748 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on estradiol (the active ingredients of Vivelle) and Vivelle (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.