Voltaren and Clonus - a phase IV clinical study of FDA data

Summary:

Clonus is reported as a side effect among people who take Voltaren (diclofenac sodium), especially for people who are male, 40-49 old, have been taking the drug for 6 - 12 months also take Cymbalta, and have Fatigue.

The phase IV clinical study analyzes which people have Clonus when taking Voltaren. It is created by eHealthMe based on reports of 81,356 people who have side effects when taking Voltaren from the FDA, and is updated regularly.

What is Voltaren?

Voltaren has active ingredients of diclofenac sodium. It is often used in arthritis. eHealthMe is studying from 82,346 Voltaren users. Check the latest studies of Voltaren.

What is Clonus?

Clonus (series of involuntary, rhythmic, muscular contractions and relaxations) is found to be associated with 300 drugs and 560 conditions by eHealthMe. Check the latest studies of Clonus.



On Jul, 04, 2026

81,356 people reported to have side effects when taking Voltaren.
Among them, 11 people (0.01%) have Clonus.

Could Voltaren cause Clonus?

Among these 11 people:

How long have people been on Voltaren when they have Clonus? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 100 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Clonus when taking Voltaren? *

  • female: 45.45 %
  • male: 54.55 %

What is the age of people who have Clonus when taking Voltaren? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 18.18 %
  • 30-39: 0.0 %
  • 40-49: 36.36 %
  • 50-59: 18.18 %
  • 60+: 27.27 %

What are other drugs people take besides Voltaren? *

  1. Cymbalta: 6 people, 54.55%
  2. Marinol: 4 people, 36.36%
  3. Provigil: 4 people, 36.36%
  4. Vitamin D: 4 people, 36.36%
  5. Vitamin B6: 4 people, 36.36%
  6. Emgality: 4 people, 36.36%
  7. Tysabri: 4 people, 36.36%
  8. Percocet: 3 people, 27.27%
  9. Effient: 2 people, 18.18%
  10. Fragmin: 2 people, 18.18%

What are other side effects people have besides Clonus? *

  1. Weakness: 6 people, 54.55%
  2. Neurogenic Bladder (the normal function of the bladder is to store and empty urine in a coordinated, controlled fashion): 6 people, 54.55%
  3. Constipation: 6 people, 54.55%
  4. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 6 people, 54.55%
  5. The Flu (the flu is caused by an influenza virus): 6 people, 54.55%
  6. Fatigue (feeling of tiredness): 6 people, 54.55%
  7. Tremor (trembling or shaking movements in one or more parts of your body): 5 people, 45.45%
  8. Major Depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings): 4 people, 36.36%
  9. Facial Spasm (involuntary muscle contractions face): 4 people, 36.36%
  10. Confusional State: 4 people, 36.36%

What are the existing conditions these people have? *

  1. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 4 people, 36.36%
  2. Fatigue (feeling of tiredness): 4 people, 36.36%
  3. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 18.18%
  4. Muscle Spasms (muscle contraction): 2 people, 18.18%
  5. Laxative Supportive Care: 2 people, 18.18%
  6. Drowsiness: 2 people, 18.18%
  7. Constipation: 2 people, 18.18%
  8. Spinal Cord Trauma: 1 person, 9.09%
  9. Muscle Spasticity (tight or stiff muscles and an inability to control those muscles): 1 person, 9.09%
  10. Insomnia (sleeplessness): 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Voltaren and have Clonus?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Voltaren:

Clonus treatments and more:

How severe was Clonus and when was it recovered:

Expand to all the drugs that have ingredients of diclofenac sodium:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Voltaren:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Clonus:

Browse all the conditions that are associated with Clonus:


How the study uses the data?

The study uses data from the FDA. It is based on diclofenac sodium (the active ingredients of Voltaren) and Voltaren (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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