Voltaren and Temperature intolerance - a phase IV clinical study of FDA data

Summary:

Temperature intolerance is reported as a side effect among people who take Voltaren (diclofenac sodium), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Neurontin, and have Multiple sclerosis.

The phase IV clinical study analyzes which people have Temperature intolerance when taking Voltaren. It is created by eHealthMe based on reports of 81,356 people who have side effects when taking Voltaren from the FDA, and is updated regularly.

What is Voltaren?

Voltaren has active ingredients of diclofenac sodium. It is often used in arthritis. eHealthMe is studying from 82,346 Voltaren users. Check the latest studies of Voltaren.

What is Temperature intolerance?

Temperature intolerance (inability to go in temperature) is found to be associated with 824 drugs and 754 conditions by eHealthMe. Check the latest studies of Temperature intolerance.



On Jul, 06, 2026

81,356 people reported to have side effects when taking Voltaren.
Among them, 24 people (0.03%) have Temperature intolerance.

Could Voltaren cause Temperature intolerance?

Among these 24 people:

How long have people been on Voltaren when they have Temperature intolerance? *

  • < 1 month: 50 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 50 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Temperature intolerance when taking Voltaren? *

  • female: 70.83 %
  • male: 29.17 %

What is the age of people who have Temperature intolerance when taking Voltaren? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 20 %
  • 40-49: 30 %
  • 50-59: 15 %
  • 60+: 35 %

What are other drugs people take besides Voltaren? *

  1. Neurontin: 8 people, 33.33%
  2. Cymbalta: 7 people, 29.17%
  3. Celebrex: 7 people, 29.17%
  4. Melatonin: 6 people, 25.00%
  5. Xanax: 6 people, 25.00%
  6. Lidoderm: 6 people, 25.00%
  7. Ambien: 6 people, 25.00%
  8. Aspirin: 6 people, 25.00%
  9. Dilaudid: 5 people, 20.83%
  10. Clonazepam: 5 people, 20.83%

What are other side effects people have besides Temperature intolerance? *

  1. Fatigue (feeling of tiredness): 12 people, 50.00%
  2. Stress And Anxiety: 10 people, 41.67%
  3. Joint Pain: 10 people, 41.67%
  4. Drug Ineffective: 9 people, 37.50%
  5. Weakness: 8 people, 33.33%
  6. Depression: 8 people, 33.33%
  7. High Blood Pressure: 8 people, 33.33%
  8. Pain In Extremity: 8 people, 33.33%
  9. Diarrhea Haemorrhagic: 7 people, 29.17%
  10. Fall: 7 people, 29.17%

What are the existing conditions these people have? *

  1. Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 3 people, 12.50%
  2. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 12.50%
  3. Renal Cell Carcinoma (a kidney cancer): 2 people, 8.33%
  4. Osteoporosis (bones weak and more likely to break): 2 people, 8.33%
  5. Hiv Infection: 2 people, 8.33%
  6. Urinary Tract Infection: 1 person, 4.17%
  7. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 1 person, 4.17%
  8. Bladder Irritation: 1 person, 4.17%
  9. Blood Potassium Decreased: 1 person, 4.17%
  10. Burning Sensation: 1 person, 4.17%

* Approximation only. Some reports may have incomplete information.

Do you take Voltaren and have Temperature intolerance?

- Check whether Temperature intolerance is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Voltaren:

Temperature intolerance treatments and more:

How severe was Temperature intolerance and when was it recovered:

Expand to all the drugs that have ingredients of diclofenac sodium:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Voltaren:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Temperature intolerance:

Browse all the conditions that are associated with Temperature intolerance:


How the study uses the data?

The study uses data from the FDA. It is based on diclofenac sodium (the active ingredients of Voltaren) and Voltaren (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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