Vortioxetine and Myoclonus - a phase IV clinical study of FDA data

Summary:

Myoclonus is reported as a side effect among people who take Vortioxetine (vortioxetine), especially for people who are female, 30-39 old, have been taking the drug for < 1 month also take Lansoprazole, and have Depression.

The phase IV clinical study analyzes which people have Myoclonus when taking Vortioxetine. It is created by eHealthMe based on reports of 2,398 people who have side effects when taking Vortioxetine from the FDA, and is updated regularly.

What is Vortioxetine?

Vortioxetine has active ingredients of vortioxetine. eHealthMe is studying from 2,440 Vortioxetine users. Check the latest studies of Vortioxetine.

What is Myoclonus?

Myoclonus (a brief, involuntary twitching of a muscle or a group of muscles) is found to be associated with 758 drugs and 1,139 conditions by eHealthMe. Check the latest studies of Myoclonus.

On Jul, 13, 2026

2,398 people reported to have side effects when taking Vortioxetine.
Among them, 12 people (0.5%) have Myoclonus.

Among these 12 people:

How long have people been on Vortioxetine when they have Myoclonus? *

What is the gender of people who have Myoclonus when taking Vortioxetine? *

female: 91.67 %
male: 8.33 %

What is the age of people who have Myoclonus when taking Vortioxetine? *

What are other drugs people take besides Vortioxetine? *

Acetaminophen: 6 people, 50.00%
Ramipril: 6 people, 50.00%
Calcium Carbonate: 6 people, 50.00%
Fentanyl: 6 people, 50.00%
Lansoprazole: 6 people, 50.00%
Ondansetron: 5 people, 41.67%
Escitalopram: 3 people, 25.00%
Lamotrigine: 2 people, 16.67%
Venlafaxine Hydrochloride: 2 people, 16.67%
Gabapentin: 2 people, 16.67%

What are other side effects people have besides Myoclonus? *

Serotonin Syndrome (occurs when two drugs that affect the body's level of serotonin are taken together at the same time): 9 people, 75.00%
Arrhythmias (irregular heartbeat): 7 people, 58.33%
High Blood Pressure: 7 people, 58.33%
Muscle Rigidity (muscle stiffness): 6 people, 50.00%
Drowsiness: 3 people, 25.00%
Encephalopathy (functioning of the brain is affected by some agent or condition): 3 people, 25.00%
Depressed Level Of Consciousness: 2 people, 16.67%
Hyperreflexia (overactive or over responsive reflexes): 2 people, 16.67%
Loss Of Consciousness: 2 people, 16.67%
Agitation (state of anxiety or nervous excitement): 2 people, 16.67%

What are the existing conditions these people have? *

Depression: 7 people, 58.33%
General Anaesthesia: 5 people, 41.67%
Ill-Defined Disorder: 4 people, 33.33%
Major Depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings): 2 people, 16.67%
Stress And Anxiety: 1 person, 8.33%
Staphylococcal Infection (an infection with staphylococcus bacteria): 1 person, 8.33%
Rickets (softening of bones): 1 person, 8.33%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 1 person, 8.33%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 1 person, 8.33%
High Blood Pressure: 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Vortioxetine and have Myoclonus?

- Check whether Myoclonus is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Vortioxetine:

Vortioxetine (2,440 reports)

Myoclonus treatments and more:

Myoclonus (14,211 reports)

Browse all side effects of Vortioxetine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Myoclonus:

Myoclonus (758 drugs)

Browse all the conditions that are associated with Myoclonus:

Myoclonus (1,139 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on vortioxetine (the active ingredients of Vortioxetine) and Vortioxetine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.