Vortioxetine and Sedation - a phase IV clinical study of FDA data

Summary:

Sedation is reported as a side effect among people who take Vortioxetine (vortioxetine), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Allopurinol, and have Depression.

The phase IV clinical study analyzes which people have Sedation when taking Vortioxetine. It is created by eHealthMe based on reports of 2,398 people who have side effects when taking Vortioxetine from the FDA, and is updated regularly.

What is Vortioxetine?

Vortioxetine has active ingredients of vortioxetine. eHealthMe is studying from 2,440 Vortioxetine users. Check the latest studies of Vortioxetine.

What is Sedation?

Sedation is found to be associated with 1,318 drugs and 1,290 conditions by eHealthMe. Check the latest studies of Sedation.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 29, 2026

2,398 people reported to have side effects when taking Vortioxetine.
Among them, 67 people (2.79%) have Sedation.

Among these 67 people:

How long have people been on Vortioxetine when they have Sedation? *

What is the gender of people who have Sedation when taking Vortioxetine? *

female: 92.06 %
male: 7.94 %

What is the age of people who have Sedation when taking Vortioxetine? *

What are other drugs people take besides Vortioxetine? *

What are other side effects people have besides Sedation? *

Dizziness: 50 people, 74.63%
Nausea (feeling of having an urge to vomit): 48 people, 71.64%
Fall: 44 people, 65.67%
Cognitive Disorder (mental health disorders affects learning, memory, perception, and problem solving): 43 people, 64.18%
Hypoglycemia (low blood sugar): 43 people, 64.18%
Hypotension (abnormally low blood pressure): 43 people, 64.18%
Fainting (loss of consciousness and postural tone): 43 people, 64.18%
Osteoporosis (bones weak and more likely to break): 43 people, 64.18%
Itching: 42 people, 62.69%
Melaena (the passage of black, tarry stools): 42 people, 62.69%

What are the existing conditions these people have? *

Depression: 56 people, 83.58%
High Blood Pressure: 44 people, 65.67%
Cardiac Failure: 42 people, 62.69%
Type 2 Diabetes: 42 people, 62.69%
Constipation: 38 people, 56.72%
Pain: 38 people, 56.72%
Abdominal Pain Upper: 17 people, 25.37%
Nasopharyngitis (inflammation of the nasopharynx): 17 people, 25.37%
Hyperglycemia (high blood sugar): 16 people, 23.88%
Coronary Heart Disease (narrowing or blockage of the coronary arteries): 15 people, 22.39%

* Approximation only. Some reports may have incomplete information.

Do you take Vortioxetine and have Sedation?

- Check whether Sedation is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Vortioxetine:

Vortioxetine (2,440 reports)

Sedation treatments and more:

Sedation (52,223 reports)

Browse all side effects of Vortioxetine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Sedation:

Sedation (1,318 drugs)

Browse all the conditions that are associated with Sedation:

Sedation (1,290 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on vortioxetine (the active ingredients of Vortioxetine) and Vortioxetine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.