Vraylar and Sleep disorder - a phase IV clinical study of FDA data

Summary:

Sleep disorder is reported as a side effect among people who take Vraylar (cariprazine hydrochloride), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Dupixent, and have Dermatitis atopic.

The phase IV clinical study analyzes which people have Sleep disorder when taking Vraylar. It is created by eHealthMe based on reports of 5,938 people who have side effects when taking Vraylar from the FDA, and is updated regularly.

What is Vraylar?

Vraylar has active ingredients of cariprazine hydrochloride. eHealthMe is studying from 6,136 Vraylar users. Check the latest studies of Vraylar.

What is Sleep disorder?

Sleep disorder is found to be associated with 2,099 drugs and 2,943 conditions by eHealthMe. Check the latest studies of Sleep disorder.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 27, 2026

5,938 people reported to have side effects when taking Vraylar.
Among them, 58 people (0.98%) have Sleep disorder.

Among these 58 people:

How long have people been on Vraylar when they have Sleep disorder? *

What is the gender of people who have Sleep disorder when taking Vraylar? *

female: 59.26 %
male: 40.74 %

What is the age of people who have Sleep disorder when taking Vraylar? *

What are other drugs people take besides Vraylar? *

What are other side effects people have besides Sleep disorder? *

Fatigue (feeling of tiredness): 10 people, 17.24%
Nightmares (unpleasant dreams): 7 people, 12.07%
Depression: 7 people, 12.07%
Rashes (redness): 6 people, 10.34%
Discomfort: 6 people, 10.34%
Drowsiness: 6 people, 10.34%
Dermatitis Atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder): 6 people, 10.34%
Stress And Anxiety: 5 people, 8.62%
Insomnia (sleeplessness): 5 people, 8.62%
Itching: 5 people, 8.62%

What are the existing conditions these people have? *

Bipolar Disorder (mood disorder): 9 people, 15.52%
Dermatitis Atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder): 9 people, 15.52%
Stress And Anxiety: 6 people, 10.34%
Bipolar I Disorder (mood disorder that is characterized by at least one manic or mixed episode): 6 people, 10.34%
Depression: 5 people, 8.62%
Tremor (trembling or shaking movements in one or more parts of your body): 2 people, 3.45%
Extrapyramidal Disorder (involuntary muscle spasms in the face and neck): 2 people, 3.45%
Autism Spectrum Disorder (developmental disabilities that can cause significant social, communication and behavioural challenges): 2 people, 3.45%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 2 people, 3.45%
Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it): 2 people, 3.45%

* Approximation only. Some reports may have incomplete information.

Do you take Vraylar and have Sleep disorder?

- Check whether Sleep disorder is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Vraylar:

Vraylar (6,136 reports)

Sleep disorder treatments and more:

Sleep disorder (167,338 reports)

Browse all side effects of Vraylar:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Sleep disorder:

Sleep disorder (2,099 drugs)

Browse all the conditions that are associated with Sleep disorder:

Sleep disorder (2,943 conditions)

Related publications that referenced our studies

Lin SC, Su YC, Huang YS, Lee CC, "Zolpidem increased cancer risk in patients with sleep disorder: A 3-year follow-up study", Journal of Medical Sciences, 2016 Mar .
Lin SC, Su YC, Huang YS, Lee CC, "Zolpidem increased cancer risk in patients with sleep disorder: A 3-year follow-up study", Journal of Medical Sciences, 2016 Mar .

How the study uses the data?

The study uses data from the FDA. It is based on cariprazine hydrochloride (the active ingredients of Vraylar) and Vraylar (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.