Vyndamax and Hypervolaemia - a phase IV clinical study of FDA data

Summary:

Hypervolaemia is reported as a side effect among people who take Vyndamax (tafamidis), especially for people who are male, 60+ old, have been taking the drug for 6 - 12 months also take Furosemide, and have Cardiac amyloidosis.

The phase IV clinical study analyzes which people have Hypervolaemia when taking Vyndamax. It is created by eHealthMe based on reports of 7,874 people who have side effects when taking Vyndamax from the FDA, and is updated regularly.

What is Vyndamax?

Vyndamax has active ingredients of tafamidis. eHealthMe is studying from 7,877 Vyndamax users. Check the latest studies of Vyndamax.

What is Hypervolaemia?

Hypervolaemia (abnormally increased volume of blood) is found to be associated with 381 drugs and 223 conditions by eHealthMe. Check the latest studies of Hypervolaemia.

On Jul, 17, 2026

7,874 people reported to have side effects when taking Vyndamax.
Among them, 14 people (0.18%) have Hypervolaemia.

Among these 14 people:

How long have people been on Vyndamax when they have Hypervolaemia? *

What is the gender of people who have Hypervolaemia when taking Vyndamax? *

female: 21.43 %
male: 78.57 %

What is the age of people who have Hypervolaemia when taking Vyndamax? *

What are other drugs people take besides Vyndamax? *

What are other side effects people have besides Hypervolaemia? *

Dyspnea (difficult or laboured breathing): 7 people, 50.00%
Abdominal Distension: 3 people, 21.43%
Oedema Peripheral (superficial swelling): 3 people, 21.43%
Fall: 3 people, 21.43%
Stress And Anxiety: 3 people, 21.43%
Hair Loss: 3 people, 21.43%
Dizziness: 3 people, 21.43%
Cardiac Failure Acute: 3 people, 21.43%
Hypovolaemia (a decreased volume of circulating blood in the body): 3 people, 21.43%
Pain: 3 people, 21.43%

What are the existing conditions these people have? *

Cardiac Amyloidosis (protein deposition in heart): 8 people, 57.14%
Amyloidosis (a tumour within which amyloid is produced): 3 people, 21.43%
Wheezing (a high-pitched whistling sound made while you breath): 1 person, 7.14%
Osteomyelitis (infection of bone): 1 person, 7.14%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 1 person, 7.14%
Cardiac Disorder: 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Vyndamax and have Hypervolaemia?

- Check whether Hypervolaemia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Vyndamax:

Vyndamax (7,877 reports)

Hypervolaemia treatments and more:

Hypervolaemia (3,872 reports)

Browse all side effects of Vyndamax:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hypervolaemia:

Hypervolaemia (381 drugs)

Browse all the conditions that are associated with Hypervolaemia:

Hypervolaemia (223 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on tafamidis (the active ingredients of Vyndamax) and Vyndamax (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.