Vyxeos and Septic shock - a phase IV clinical study of FDA data

Summary:

Septic shock is reported as a side effect among people who take Vyxeos (cytarabine; daunorubicin), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Valacyclovir Hydrochloride, and have Acute myeloid leukaemia.

The phase IV clinical study analyzes which people have Septic shock when taking Vyxeos. It is created by eHealthMe based on reports of 1,217 people who have side effects when taking Vyxeos from the FDA, and is updated regularly.

What is Vyxeos?

Vyxeos has active ingredients of cytarabine; daunorubicin. eHealthMe is studying from 1,217 Vyxeos users. Check the latest studies of Vyxeos.

What is Septic shock?

Septic shock (shock due to blood infection) is found to be associated with 1,740 drugs and 3,396 conditions by eHealthMe. Check the latest studies of Septic shock.

On Jul, 28, 2026

1,217 people reported to have side effects when taking Vyxeos.
Among them, 44 people (3.62%) have Septic shock.

Among these 44 people:

How long have people been on Vyxeos when they have Septic shock? *

What is the gender of people who have Septic shock when taking Vyxeos? *

female: 68.97 %
male: 31.03 %

What is the age of people who have Septic shock when taking Vyxeos? *

What are other drugs people take besides Vyxeos? *

Valacyclovir Hydrochloride: 18 people, 40.91%
Ondansetron: 17 people, 38.64%
Acetaminophen: 16 people, 36.36%
Pantoprazole: 15 people, 34.09%
Metoclopramide: 10 people, 22.73%
Allopurinol: 10 people, 22.73%
Posaconazole: 10 people, 22.73%
Ceftriaxone: 10 people, 22.73%
Aprepitant: 7 people, 15.91%
Dexamethasone: 7 people, 15.91%

What are other side effects people have besides Septic shock? *

Acute Pulmonary Oedema (sudden deposit of fluid in the lung)): 10 people, 22.73%
Ards (Acute Respiratory Distress Syndrome) (sudden failure of the respiratory (breathing) system): 10 people, 22.73%
Stenotrophomonas Infection: 8 people, 18.18%
Pseudomonas Infection (pseudomonas infection is caused by a bacterium, pseudomonas aeruginosa): 8 people, 18.18%
Dermo-Hypodermitis (skin and subcutaneous tissue bacterial infections): 8 people, 18.18%
Erysipelas (bacterial skin infection): 8 people, 18.18%
Aplasia (defective development or congenital absence of an organ or tissue): 7 people, 15.91%
Cardiogenic Shock (inadequate circulation of blood): 7 people, 15.91%
Fever: 7 people, 15.91%
Weight Increased: 6 people, 13.64%

What are the existing conditions these people have? *

Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 41 people, 93.18%
Infection: 24 people, 54.55%
Nausea (feeling of having an urge to vomit): 16 people, 36.36%
Pain: 10 people, 22.73%
Nausea And Vomiting: 7 people, 15.91%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 7 people, 15.91%
Hyperchlorhydria (gastric acid levels are higher in stomach): 7 people, 15.91%
High Blood Pressure: 7 people, 15.91%
Diarrhea Infectious: 7 people, 15.91%
Diarrhea: 7 people, 15.91%

* Approximation only. Some reports may have incomplete information.

Do you take Vyxeos and have Septic shock?

- Check whether Septic shock is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Vyxeos:

Vyxeos (1,217 reports)

Septic shock treatments and more:

Septic shock (51,128 reports)

Browse all side effects of Vyxeos:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Septic shock:

Septic shock (1,740 drugs)

Browse all the conditions that are associated with Septic shock:

Septic shock (3,396 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on cytarabine; daunorubicin (the active ingredients of Vyxeos) and Vyxeos (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.