Vyzulta and Cough aggravated - a phase IV clinical study of FDA data

Summary:

Cough aggravated is reported as a side effect among people who take Vyzulta (latanoprostene bunod), especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months also take Brimonidine Tartrate, and have High blood pressure.

The phase IV clinical study analyzes which people have Cough aggravated when taking Vyzulta. It is created by eHealthMe based on reports of 731 people who have side effects when taking Vyzulta from the FDA, and is updated regularly.

What is Vyzulta?

Vyzulta has active ingredients of latanoprostene bunod. It is often used in glaucoma. eHealthMe is studying from 740 Vyzulta users. Check the latest studies of Vyzulta.

What is Cough aggravated?

Cough aggravated is found to be associated with 2,461 drugs and 905 conditions by eHealthMe. Check the latest studies of Cough aggravated.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 26, 2026

731 people reported to have side effects when taking Vyzulta.
Among them, 12 people (1.64%) have Cough aggravated.

Among these 12 people:

How long have people been on Vyzulta when they have Cough aggravated? *

What is the gender of people who have Cough aggravated when taking Vyzulta? *

female: 90.91 %
male: 9.09 %

What is the age of people who have Cough aggravated when taking Vyzulta? *

What are other drugs people take besides Vyzulta? *

Brimonidine Tartrate: 4 people, 33.33%
Vitamin D3: 3 people, 25.00%
Vitamin B12: 3 people, 25.00%
Allegra Allergy: 3 people, 25.00%
Aspirin: 3 people, 25.00%
Epinephrine: 3 people, 25.00%
Lisinopril: 2 people, 16.67%
Duloxetine Hydrochloride: 2 people, 16.67%
Potassium: 2 people, 16.67%
Nifedipine: 2 people, 16.67%

What are other side effects people have besides Cough aggravated? *

Headache (pain in head): 5 people, 41.67%
Oropharyngeal Pain: 4 people, 33.33%
Nasal Congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels): 4 people, 33.33%
Sinus Headache (headache caused by sinus infections): 3 people, 25.00%
Malaise (a feeling of general discomfort or uneasiness): 3 people, 25.00%
Pain: 3 people, 25.00%
Infusion Site Pruritus (severe itching at infusion site): 2 people, 16.67%
Laryngitis (inflammation of the larynx): 2 people, 16.67%
Joint Pain: 2 people, 16.67%
Insomnia (sleeplessness): 2 people, 16.67%

What are the existing conditions these people have? *

Immunodeficiency Common Variable: 2 people, 16.67%
Immunodeficiency: 2 people, 16.67%
High Blood Pressure: 2 people, 16.67%
Type 1 Diabetes: 1 person, 8.33%
Retinal Detachment (a disorder of the eye in which the retina peels away from its underlying layer of support tissue): 1 person, 8.33%
Pulmonary Haematoma (collection of blood within the tissue of the lung): 1 person, 8.33%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 1 person, 8.33%
Ovarian Cancer (cancer of ovary): 1 person, 8.33%
Macular Degeneration (painless eye condition that leads to the gradual loss of central vision): 1 person, 8.33%
Joint Pain: 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Vyzulta and have Cough aggravated?

- Check whether Cough aggravated is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Vyzulta:

Vyzulta (740 reports)

Browse all side effects of Vyzulta:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Cough aggravated:

Cough aggravated (2,461 drugs)

Browse all the conditions that are associated with Cough aggravated:

Cough aggravated (905 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on latanoprostene bunod (the active ingredients of Vyzulta) and Vyzulta (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.