Vyzulta and Pain - a phase IV clinical study of FDA data

Summary:

Pain is reported as a side effect among people who take Vyzulta (latanoprostene bunod), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Simbrinza, and have Mikulicz's syndrome.

The phase IV clinical study analyzes which people have Pain when taking Vyzulta. It is created by eHealthMe based on reports of 731 people who have side effects when taking Vyzulta from the FDA, and is updated regularly.

What is Vyzulta?

Vyzulta has active ingredients of latanoprostene bunod. It is often used in glaucoma. eHealthMe is studying from 740 Vyzulta users. Check the latest studies of Vyzulta.

What is Pain?

Pain is found to be associated with 3,815 drugs and 5,866 conditions by eHealthMe. Check the latest studies of Pain.

On Jul, 19, 2026

731 people reported to have side effects when taking Vyzulta.
Among them, 36 people (4.92%) have Pain.

Among these 36 people:

How long have people been on Vyzulta when they have Pain? *

What is the gender of people who have Pain when taking Vyzulta? *

female: 89.66 %
male: 10.34 %

What is the age of people who have Pain when taking Vyzulta? *

What are other drugs people take besides Vyzulta? *

What are other side effects people have besides Pain? *

Joint Pain: 18 people, 50.00%
Rashes (redness): 14 people, 38.89%
Blood Urine Present: 12 people, 33.33%
Vitreous Floaters (spots before the eyes): 12 people, 33.33%
Kidney Stones: 12 people, 33.33%
Joint Stiffness: 12 people, 33.33%
Stress And Anxiety: 7 people, 19.44%
Drowsiness: 6 people, 16.67%
Infusion Related Reaction: 6 people, 16.67%
Headache (pain in head): 6 people, 16.67%

What are the existing conditions these people have? *

Mikulicz's Syndrome (abnormal enlargement of glands in the head and neck): 12 people, 33.33%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 4 people, 11.11%
Cardiac Disorder: 2 people, 5.56%
Immunodeficiency Common Variable: 2 people, 5.56%
Immunodeficiency: 2 people, 5.56%
Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 1 person, 2.78%
Dry Eyes (lack of adequate tears): 1 person, 2.78%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 1 person, 2.78%
Colitis (inflammation of colon): 1 person, 2.78%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 1 person, 2.78%

* Approximation only. Some reports may have incomplete information.

Do you take Vyzulta and have Pain?

- Check whether Pain is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Vyzulta:

Vyzulta (740 reports)

Pain treatments and more:

Pain (1,140,594 reports)

Browse all side effects of Vyzulta:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Pain:

Pain (3,815 drugs)

Browse all the conditions that are associated with Pain:

Pain (5,866 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on latanoprostene bunod (the active ingredients of Vyzulta) and Vyzulta (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.