Warfarin sodium and Bipolar disorder - a phase IV clinical study of FDA data

Summary:

Bipolar disorder is reported as a side effect among people who take Warfarin sodium (warfarin sodium), especially for people who are female, 50-59 old, also take Serevent, and have Heart rate irregular.

The phase IV clinical study analyzes which people have Bipolar disorder when taking Warfarin sodium. It is created by eHealthMe based on reports of 67,331 people who have side effects when taking Warfarin sodium from the FDA, and is updated regularly.

What is Warfarin sodium?

Warfarin sodium has active ingredients of warfarin sodium. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 71,174 Warfarin sodium users. Check the latest studies of Warfarin sodium.

What is Bipolar disorder?

Bipolar disorder (mood disorder) is found to be associated with 910 drugs and 1,231 conditions by eHealthMe. Check the latest studies of Bipolar disorder.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 18, 2026

67,331 people reported to have side effects when taking Warfarin sodium.
Among them, 20 people (0.03%) have Bipolar disorder.

Could Warfarin sodium cause Bipolar disorder?

Among these 20 people:

What is the gender of people who have Bipolar disorder when taking Warfarin sodium? *

female: 75 %
male: 25 %

What is the age of people who have Bipolar disorder when taking Warfarin sodium? *

What are other drugs people take besides Warfarin sodium? *

What are other side effects people have besides Bipolar disorder? *

Stress And Anxiety: 13 people, 65.00%
Depression: 12 people, 60.00%
Chest Pain: 8 people, 40.00%
Nausea (feeling of having an urge to vomit): 5 people, 25.00%
Pain: 5 people, 25.00%
Intervertebral Disc Protrusion (spinal disc protrusion): 5 people, 25.00%
Heart Attack: 4 people, 20.00%
Neuropathy Peripheral (surface nerve damage): 4 people, 20.00%
High Blood Cholesterol: 4 people, 20.00%
Upper Limb Fracture: 4 people, 20.00%

What are the existing conditions these people have? *

Heart Rate Irregular: 4 people, 20.00%
Alveolitis Allergic (inflammation of the alveoli within the lung caused by hypersensitivity to inhaled organic dusts): 3 people, 15.00%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 15.00%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 15.00%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 3 people, 15.00%
High Blood Cholesterol: 3 people, 15.00%
Stress And Anxiety: 2 people, 10.00%
Thrombosis (formation of a blood clot inside a blood vessel): 2 people, 10.00%
Pain: 2 people, 10.00%
Hypertonic Bladder (bladder-storage function that causes a sudden urge to urinate): 2 people, 10.00%

* Approximation only. Some reports may have incomplete information.

Do you take Warfarin sodium and have Bipolar disorder?

- Check whether Bipolar disorder is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Warfarin sodium:

Warfarin sodium (71,174 reports)

Bipolar disorder treatments and more:

Bipolar disorder (109,430 reports)

Browse all side effects of Warfarin sodium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Bipolar disorder:

Bipolar disorder (910 drugs)

Browse all the conditions that are associated with Bipolar disorder:

Bipolar disorder (1,231 conditions)

Related publications that referenced our studies

Ayano G, "Bipolar Disorders and Valproate: Pharmacokinetics, Pharmacodynamics and Therapeutic Effects and Indications of Valproate: Review of Articles", Bipolar Disord, 2017 Jan .
Ayano G, "Bipolar Disorders and Valproate: Pharmacokinetics, Pharmacodynamics and Therapeutic Effects and Indications of Valproate: Review of Articles", Bipolar Disord, 2017 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on warfarin sodium (the active ingredients of Warfarin sodium) and Warfarin sodium (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.