Wegovy and Gallstones - a phase IV clinical study of FDA data

Summary:

Gallstones is reported as a side effect among people who take Wegovy (semaglutide), especially for people who are female, 50-59 old, have been taking the drug for < 1 month also take Sertraline, and have Weight decreased.

The phase IV clinical study analyzes which people have Gallstones when taking Wegovy. It is created by eHealthMe based on reports of 4,836 people who have side effects when taking Wegovy from the FDA, and is updated regularly.

What is Wegovy?

Wegovy has active ingredients of semaglutide. It is often used in weight loss. eHealthMe is studying from 4,886 Wegovy users. Check the latest studies of Wegovy.

What is Gallstones?

Gallstones (stone formation by bile component) is found to be associated with 1,810 drugs and 2,098 conditions by eHealthMe. Check the latest studies of Gallstones.

On Aug, 02, 2026

4,836 people reported to have side effects when taking Wegovy.
Among them, 41 people (0.85%) have Gallstones.

Among these 41 people:

How long have people been on Wegovy when they have Gallstones? *

What is the gender of people who have Gallstones when taking Wegovy? *

female: 89.74 %
male: 10.26 %

What is the age of people who have Gallstones when taking Wegovy? *

What are other drugs people take besides Wegovy? *

What are other side effects people have besides Gallstones? *

Pancreatitis (inflammation of pancreas): 6 people, 14.63%
Weight Decreased: 4 people, 9.76%
Cholecystitis (infection of gallbladder): 4 people, 9.76%
Gastrointestinal Disorder (functional problems of gastrointestinal tract): 4 people, 9.76%
Pneumonia: 3 people, 7.32%
Influenza Like Illness: 3 people, 7.32%
Post Procedural Infection: 3 people, 7.32%
Upper Limb Fracture: 3 people, 7.32%
Diarrhea: 3 people, 7.32%
Melanocytic Naevus (a type of lesion that contains nevus cells (a type of melanocyte)): 3 people, 7.32%

What are the existing conditions these people have? *

Weight Decreased: 10 people, 24.39%
Ankylosing Spondylitis (type of arthritis affecting the spine): 3 people, 7.32%
Polycystic Ovary Disease (cysts in the ovaries that occurs when the follicle stops developing): 1 person, 2.44%
Depression: 1 person, 2.44%
Asthma: 1 person, 2.44%

* Approximation only. Some reports may have incomplete information.

Do you take Wegovy and have Gallstones?

- Check whether Gallstones is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Wegovy:

Wegovy (4,886 reports)

Gallstones treatments and more:

Gallstones (50,126 reports)

Browse all side effects of Wegovy:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Gallstones:

Gallstones (1,810 drugs)

Browse all the conditions that are associated with Gallstones:

Gallstones (2,098 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on semaglutide (the active ingredients of Wegovy) and Wegovy (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.