Wellbutrin xl and Bruxism - a phase IV clinical study of FDA data

Summary:

Bruxism is reported as a side effect among people who take Wellbutrin xl (bupropion hydrochloride), especially for people who are female, 40-49 old, have been taking the drug for < 1 month also take Ritalin, and have Attention deficit hyperactivity disorder.

The phase IV clinical study analyzes which people have Bruxism when taking Wellbutrin xl. It is created by eHealthMe based on reports of 18,200 people who have side effects when taking Wellbutrin xl from the FDA, and is updated regularly.

What is Wellbutrin xl?

Wellbutrin xl has active ingredients of bupropion hydrochloride. It is often used in depression. eHealthMe is studying from 22,996 Wellbutrin xl users. Check the latest studies of Wellbutrin xl.

What is Bruxism?

Bruxism (habitual grinding of the teeth, typically during sleep) is found to be associated with 589 drugs and 981 conditions by eHealthMe. Check the latest studies of Bruxism.

On Jul, 04, 2026

18,200 people reported to have side effects when taking Wellbutrin xl.
Among them, 39 people (0.21%) have Bruxism.

Among these 39 people:

How long have people been on Wellbutrin xl when they have Bruxism? *

What is the gender of people who have Bruxism when taking Wellbutrin xl? *

female: 80.56 %
male: 19.44 %

What is the age of people who have Bruxism when taking Wellbutrin xl? *

What are other drugs people take besides Wellbutrin xl? *

What are other side effects people have besides Bruxism? *

Tremor (trembling or shaking movements in one or more parts of your body): 9 people, 23.08%
Insomnia (sleeplessness): 8 people, 20.51%
Dry Mouth: 5 people, 12.82%
Agitation (state of anxiety or nervous excitement): 4 people, 10.26%
Headache (pain in head): 4 people, 10.26%
Hyperhidrosis (abnormally increased sweating): 4 people, 10.26%
Heart Palpitations (feelings or sensations that your heart is pounding or racing): 4 people, 10.26%
Memory Loss: 3 people, 7.69%
Malaise (a feeling of general discomfort or uneasiness): 2 people, 5.13%
High Blood Pressure: 2 people, 5.13%

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 2 people, 5.13%
Attention Deficit Hyperactivity Disorder (a chronic condition including attention difficulty, hyperactivity, and impulsiveness): 2 people, 5.13%
Seasonal Affective Disorder (a type of depression that occurs at a certain time of the year, usually in the winter): 1 person, 2.56%
Erection Problems: 1 person, 2.56%
Blood Prolactin Increased: 1 person, 2.56%

* Approximation only. Some reports may have incomplete information.

Do you take Wellbutrin xl and have Bruxism?

- Check whether Bruxism is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Wellbutrin xl:

Wellbutrin xl (22,996 reports)

Bruxism treatments and more:

Bruxism (7,187 reports)

Browse all side effects of Wellbutrin xl:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Bruxism:

Bruxism (589 drugs)

Browse all the conditions that are associated with Bruxism:

Bruxism (981 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on bupropion hydrochloride (the active ingredients of Wellbutrin xl) and Wellbutrin xl (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.