Wellbutrin xl and Itching - a phase IV clinical study of FDA data

Summary:

Itching is reported as a side effect among people who take Wellbutrin xl (bupropion hydrochloride), especially for people who are female, 40-49 old, have been taking the drug for < 1 month also take Cymbalta, and have Immunodeficiency common variable.

The phase IV clinical study analyzes which people have Itching when taking Wellbutrin xl. It is created by eHealthMe based on reports of 18,200 people who have side effects when taking Wellbutrin xl from the FDA, and is updated regularly.

What is Wellbutrin xl?

Wellbutrin xl has active ingredients of bupropion hydrochloride. It is often used in depression. eHealthMe is studying from 23,002 Wellbutrin xl users. Check the latest studies of Wellbutrin xl.

What is Itching?

Itching is found to be associated with 3,211 drugs and 4,538 conditions by eHealthMe. Check the latest studies of Itching.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

18,200 people reported to have side effects when taking Wellbutrin xl.
Among them, 460 people (2.53%) have Itching.

Among these 460 people:

* Approximation only. Some reports may have incomplete information.

Do you take Wellbutrin xl and have Itching?

- Check whether Itching is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Wellbutrin xl:

Wellbutrin xl (23,002 reports)

Itching treatments and more:

Itching (398,823 reports)

How severe was Itching and when was it recovered:

Itching in Wellbutrin xl

Expand to all the drugs that have ingredients of bupropion hydrochloride:

Itching and drugs with ingredients of bupropion hydrochloride (4,459 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Wellbutrin xl:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Itching:

Itching (3,211 drugs)

Browse all the conditions that are associated with Itching:

Itching (4,538 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on bupropion hydrochloride (the active ingredients of Wellbutrin xl) and Wellbutrin xl (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.