Xadago and Rashes - a phase IV clinical study of FDA data

Summary:

Rashes is reported as a side effect among people who take Xadago (safinamide mesylate), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Nuplazid, and have Parkinson's disease.

The phase IV clinical study analyzes which people have Rashes when taking Xadago. It is created by eHealthMe based on reports of 1,020 people who have side effects when taking Xadago from the FDA, and is updated regularly.

What is Xadago?

Xadago has active ingredients of safinamide mesylate. eHealthMe is studying from 1,022 Xadago users. Check the latest studies of Xadago.

What is Rashes?

Rashes (redness) is found to be associated with 3,713 drugs and 6,213 conditions by eHealthMe. Check the latest studies of Rashes.



On Jul, 13, 2026

1,020 people reported to have side effects when taking Xadago.
Among them, 17 people (1.67%) have Rashes.

Could Xadago cause Rashes?

Among these 17 people:

How long have people been on Xadago when they have Rashes? *

  • < 1 month: 50 %
  • 1 - 6 months: 50 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Rashes when taking Xadago? *

  • female: 41.18 %
  • male: 58.82 %

What is the age of people who have Rashes when taking Xadago? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 0.0 %
  • 60+: 100 %

What are other drugs people take besides Xadago? *

  1. Nuplazid: 8 people, 47.06%
  2. Percocet: 4 people, 23.53%
  3. Vitamin B12: 4 people, 23.53%
  4. Lexapro: 4 people, 23.53%
  5. Rytary: 4 people, 23.53%
  6. Vitamin D3: 3 people, 17.65%
  7. Fish Oil: 3 people, 17.65%
  8. Vitamin C: 3 people, 17.65%
  9. Mirapex: 3 people, 17.65%
  10. Nesina: 3 people, 17.65%

What are other side effects people have besides Rashes? *

  1. Peripheral Swelling: 5 people, 29.41%
  2. Skin Discoloration: 5 people, 29.41%
  3. Ventricular Extrasystoles (premature cardiac contraction): 4 people, 23.53%
  4. Heart Palpitations (feelings or sensations that your heart is pounding or racing): 4 people, 23.53%
  5. Peripheral Coldness: 4 people, 23.53%
  6. Weakness: 3 people, 17.65%
  7. Seizures (abnormal excessive or synchronous neuronal activity in the brain): 3 people, 17.65%
  8. Hair Loss: 3 people, 17.65%
  9. Impatience (restlessness): 3 people, 17.65%
  10. Fatigue (feeling of tiredness): 3 people, 17.65%

What are the existing conditions these people have? *

  1. Parkinson's Disease: 9 people, 52.94%
  2. Hallucinations (sensations that appear real but are created by your mind): 7 people, 41.18%
  3. Delusion (a false belief or opinion): 7 people, 41.18%
  4. Type 2 Diabetes: 3 people, 17.65%
  5. Vitamin B12 Deficiency: 1 person, 5.88%
  6. Pneumonia Aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree): 1 person, 5.88%
  7. Metabolic Acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body): 1 person, 5.88%
  8. Iron Deficiency: 1 person, 5.88%
  9. Hyperthyroidism (over activity of the thyroid gland): 1 person, 5.88%
  10. High Blood Pressure: 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

Do you take Xadago and have Rashes?

- Check whether Rashes is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Xadago:

Rashes treatments and more:

How severe was Rashes and when was it recovered:

Expand to all the drugs that have ingredients of safinamide mesylate:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Xadago:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Rashes:

Browse all the conditions that are associated with Rashes:


How the study uses the data?

The study uses data from the FDA. It is based on safinamide mesylate (the active ingredients of Xadago) and Xadago (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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