Xeloda and Haematotoxicity - a phase IV clinical study of FDA data

Summary:

Haematotoxicity is reported as a side effect among people who take Xeloda (capecitabine), especially for people who are female, 60+ old, have been taking the drug for 6 - 12 months also take Herceptin, and have Colon cancer metastatic.

The phase IV clinical study analyzes which people have Haematotoxicity when taking Xeloda. It is created by eHealthMe based on reports of 46,293 people who have side effects when taking Xeloda from the FDA, and is updated regularly.

What is Xeloda?

Xeloda has active ingredients of capecitabine. It is often used in colon cancer. eHealthMe is studying from 46,649 Xeloda users. Check the latest studies of Xeloda.

What is Haematotoxicity?

Haematotoxicity (toxins that destroy red blood cells) is found to be associated with 344 drugs and 829 conditions by eHealthMe. Check the latest studies of Haematotoxicity.



On Jul, 26, 2026

46,293 people reported to have side effects when taking Xeloda.
Among them, 87 people (0.19%) have Haematotoxicity.

Could Xeloda cause Haematotoxicity?

Among these 87 people:

How long have people been on Xeloda when they have Haematotoxicity? *

  • < 1 month: 28.26 %
  • 1 - 6 months: 21.74 %
  • 6 - 12 months: 43.48 %
  • 1 - 2 years: 2.17 %
  • 2 - 5 years: 4.35 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Haematotoxicity when taking Xeloda? *

  • female: 61.25 %
  • male: 38.75 %

What is the age of people who have Haematotoxicity when taking Xeloda? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 1.59 %
  • 40-49: 20.63 %
  • 50-59: 30.16 %
  • 60+: 47.62 %

What are other drugs people take besides Xeloda? *

  1. Herceptin: 25 people, 28.74%
  2. Avastin: 14 people, 16.09%
  3. Taxol: 12 people, 13.79%
  4. Navelbine: 12 people, 13.79%
  5. Lapatinib: 11 people, 12.64%
  6. Afinitor: 11 people, 12.64%
  7. Vinorelbine: 11 people, 12.64%
  8. Kadcyla: 11 people, 12.64%
  9. Taxotere: 8 people, 9.20%
  10. Paclitaxel: 7 people, 8.05%

What are other side effects people have besides Haematotoxicity? *

  1. Diarrhea: 17 people, 19.54%
  2. Disease Progression: 16 people, 18.39%
  3. Nausea (feeling of having an urge to vomit): 14 people, 16.09%
  4. Skin Toxicity (skin damage due to toxin/poison): 13 people, 14.94%
  5. Palmar-Plantar Erythrodysaesthesia Syndrome (hand-foot syndrome): 12 people, 13.79%
  6. Thrombocytopenia (decrease of platelets in blood): 12 people, 13.79%
  7. Nausea And Vomiting: 12 people, 13.79%
  8. Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 10 people, 11.49%
  9. Ejection Fraction Abnormal (abnormality in percentage of blood that is pumped out of a filled ventricle as a result of a heartbeat): 10 people, 11.49%
  10. Neurotoxicity (when the exposure to natural or artificial toxic substances, which are called neurotoxins, alters the normal activity of the nervous system): 10 people, 11.49%

What are the existing conditions these people have? *

  1. Colon Cancer Metastatic (cancer of colon spreads to other part of body): 6 people, 6.90%
  2. Rectal Cancer (cancer of rectum): 4 people, 4.60%
  3. Rectal Cancer Metastatic (cancer of rectum spreads to other): 3 people, 3.45%
  4. Gastric Cancer (stomach cancer): 3 people, 3.45%
  5. Colorectal Cancer Metastatic (cancer of colon and rectal spreads to other parts): 2 people, 2.30%
  6. Metastases To Lymph Nodes (cancer spreads to lymph node): 2 people, 2.30%
  7. Metastases To Liver (cancer spreads to liver): 2 people, 2.30%
  8. Metastases To Bone (cancer spreads to bone): 2 people, 2.30%
  9. Dyslipidaemia (abnormal amount of lipids): 1 person, 1.15%
  10. Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 1 person, 1.15%

* Approximation only. Some reports may have incomplete information.

Do you take Xeloda and have Haematotoxicity?

- Check whether Haematotoxicity is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Xeloda:

Haematotoxicity treatments and more:

How severe was Haematotoxicity and when was it recovered:

Expand to all the drugs that have ingredients of capecitabine:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Xeloda:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Haematotoxicity:

Browse all the conditions that are associated with Haematotoxicity:

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on capecitabine (the active ingredients of Xeloda) and Xeloda (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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