Xeloda and Muscle contracture - a phase IV clinical study of FDA data

Summary:

Muscle contracture is reported as a side effect among people who take Xeloda (capecitabine), especially for people who are female, 40-49 old, have been taking the drug for < 1 month also take Herceptin, and have Breast neoplasm.

The phase IV clinical study analyzes which people have Muscle contracture when taking Xeloda. It is created by eHealthMe based on reports of 46,293 people who have side effects when taking Xeloda from the FDA, and is updated regularly.

What is Xeloda?

Xeloda has active ingredients of capecitabine. It is often used in colon cancer. eHealthMe is studying from 46,649 Xeloda users. Check the latest studies of Xeloda.

What is Muscle contracture?

Muscle contracture (a permanent shortening of a muscle) is found to be associated with 332 drugs and 523 conditions by eHealthMe. Check the latest studies of Muscle contracture.

On Jul, 09, 2026

46,293 people reported to have side effects when taking Xeloda.
Among them, 19 people (0.04%) have Muscle contracture.

Among these 19 people:

How long have people been on Xeloda when they have Muscle contracture? *

What is the gender of people who have Muscle contracture when taking Xeloda? *

female: 94.74 %
male: 5.26 %

What is the age of people who have Muscle contracture when taking Xeloda? *

What are other drugs people take besides Xeloda? *

What are other side effects people have besides Muscle contracture? *

Headache (pain in head): 14 people, 73.68%
Skin Toxicity (skin damage due to toxin/poison): 14 people, 73.68%
Disease Recurrence: 12 people, 63.16%
Radiation Pneumonitis (inflammation of lung due to radiation): 12 people, 63.16%
Disease Progression: 12 people, 63.16%
Neoplasm Recurrence (reoccurrence of tumour): 9 people, 47.37%
Neoplasm Progression (growth of tumour): 9 people, 47.37%
Hypotension (abnormally low blood pressure): 4 people, 21.05%
Musculoskeletal Stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves): 3 people, 15.79%
Neuroleptic Malignant Syndrome (a life-threatening neurological disorder most often caused by an adverse reaction to neuroleptic or antipsychotic agents): 3 people, 15.79%

What are the existing conditions these people have? *

Breast Neoplasm (non cancerous tumour of breast): 14 people, 73.68%
Depression: 3 people, 15.79%
Cancer Pain: 3 people, 15.79%
High Blood Pressure: 2 people, 10.53%
Leukopenia (less number of white blood cells in blood): 1 person, 5.26%
Indigestion: 1 person, 5.26%
High Blood Cholesterol: 1 person, 5.26%
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 1 person, 5.26%

* Approximation only. Some reports may have incomplete information.

Do you take Xeloda and have Muscle contracture?

- Check whether Muscle contracture is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Xeloda:

Xeloda (46,649 reports)

Browse all side effects of Xeloda:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Muscle contracture:

Muscle contracture (332 drugs)

Browse all the conditions that are associated with Muscle contracture:

Muscle contracture (523 conditions)

Related publications that referenced our studies

Pinto HP, Bhat RM, Shet D, Dandekeri S, "Compound mucocutaneous adverse effects of oral capecitabine in a patient", Indian dermatology online journal, 2014 Jan .
Kang SM, Baek JY, Hwangbo B, Kim HY, Lee GK, Lee HS, "A case of capecitabine-induced sarcoidosis", Tuberculosis and respiratory diseases, 2012 Mar .
Pinto HP, Bhat RM, Shet D, Dandekeri S, "Compound mucocutaneous adverse effects of oral capecitabine in a patient", Indian dermatology online journal, 2014 Jan .
Kang SM, Baek JY, Hwangbo B, Kim HY, Lee GK, Lee HS, "A case of capecitabine-induced sarcoidosis", Tuberculosis and respiratory diseases, 2012 Mar .

How the study uses the data?

The study uses data from the FDA. It is based on capecitabine (the active ingredients of Xeloda) and Xeloda (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.