Xenazine and Affective disorder - a phase IV clinical study of FDA data

Summary:

Affective disorder is reported as a side effect among people who take Xenazine (tetrabenazine), especially for people who are male, 60+ old, have been taking the drug for 6 - 12 months also take Atarax, and have Movement - unpredictable or jerky.

The phase IV clinical study analyzes which people have Affective disorder when taking Xenazine. It is created by eHealthMe based on reports of 7,291 people who have side effects when taking Xenazine from the FDA, and is updated regularly.

What is Xenazine?

Xenazine has active ingredients of tetrabenazine. eHealthMe is studying from 7,308 Xenazine users. Check the latest studies of Xenazine.

What is Affective disorder?

Affective disorder (mental disorder) is found to be associated with 709 drugs and 786 conditions by eHealthMe. Check the latest studies of Affective disorder.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 27, 2026

7,291 people reported to have side effects when taking Xenazine.
Among them, 16 people (0.22%) have Affective disorder.

Could Xenazine cause Affective disorder?

Among these 16 people:

How long have people been on Xenazine when they have Affective disorder? *

What is the gender of people who have Affective disorder when taking Xenazine? *

female: 50 %
male: 50 %

What is the age of people who have Affective disorder when taking Xenazine? *

What are other drugs people take besides Xenazine? *

Zoloft: 2 people, 12.50%
Atarax: 2 people, 12.50%
Trileptal: 1 person, 6.25%
Plavix: 1 person, 6.25%
Lactulose: 1 person, 6.25%
Gabapentin: 1 person, 6.25%
Estrogenic Substance: 1 person, 6.25%
Clonazepam: 1 person, 6.25%
Citalopram Hydrobromide: 1 person, 6.25%
Bisoprolol Fumarate: 1 person, 6.25%

What are other side effects people have besides Affective disorder? *

Depression: 5 people, 31.25%
Memory Loss: 4 people, 25.00%
Fatigue (feeling of tiredness): 4 people, 25.00%
Drowsiness: 4 people, 25.00%
Disturbance In Attention: 3 people, 18.75%
Crying: 3 people, 18.75%
Anger: 3 people, 18.75%
Balance Disorder: 3 people, 18.75%
Drug Administration Error: 2 people, 12.50%
Head Injury: 2 people, 12.50%

What are the existing conditions these people have? *

Movement - Unpredictable Or Jerky: 4 people, 25.00%
Gilles De La Tourette Syndrome (a condition that causes people to make repeated, quick movements or sounds that they cannot control): 1 person, 6.25%
Dyskinesia (abnormality or impairment of voluntary movement): 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Xenazine and have Affective disorder?

- Check whether Affective disorder is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Xenazine:

Xenazine (7,308 reports)

Browse all side effects of Xenazine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Affective disorder:

Affective disorder (709 drugs)

Browse all the conditions that are associated with Affective disorder:

Affective disorder (786 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on tetrabenazine (the active ingredients of Xenazine) and Xenazine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.