Xenical and Hyperkalemia - a phase IV clinical study of FDA data

Summary:

Hyperkalemia is reported as a side effect among people who take Xenical (orlistat), especially for people who are female, 60+ old, also take Lasix, and have Cardiac failure congestive.

The phase IV clinical study analyzes which people have Hyperkalemia when taking Xenical. It is created by eHealthMe based on reports of 11,562 people who have side effects when taking Xenical from the FDA, and is updated regularly.

What is Xenical?

Xenical has active ingredients of orlistat. It is often used in weight loss. eHealthMe is studying from 11,722 Xenical users. Check the latest studies of Xenical.

What is Hyperkalemia?

Hyperkalemia (damage to or disease of the kidney) is found to be associated with 1,956 drugs and 2,937 conditions by eHealthMe. Check the latest studies of Hyperkalemia.

On May, 01, 2026

11,562 people reported to have side effects when taking Xenical.
Among them, 24 people (0.21%) have Hyperkalemia.

Among these 24 people:

What is the gender of people who have Hyperkalemia when taking Xenical? *

female: 58.33 %
male: 41.67 %

What is the age of people who have Hyperkalemia when taking Xenical? *

What are other drugs people take besides Xenical? *

What are other side effects people have besides Hyperkalemia? *

Acute Kidney Failure: 8 people, 33.33%
Abdominal Pain Upper: 7 people, 29.17%
Multiple Injuries: 6 people, 25.00%
Liver Function Tests Nos Abnormal: 6 people, 25.00%
Pulmonary Congestion (congestion in the lungs): 6 people, 25.00%
Cardiac Failure Congestive: 6 people, 25.00%
Weight Decreased: 5 people, 20.83%
Blood Bilirubin Increased: 5 people, 20.83%
Lobar Pneumonia (a form of pneumonia that affects a large and continuous area of the lobe of a lung): 5 people, 20.83%
Fatty Liver: 5 people, 20.83%

What are the existing conditions these people have? *

Cardiac Failure Congestive: 3 people, 12.50%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 1 person, 4.17%

* Approximation only. Some reports may have incomplete information.

Do you take Xenical and have Hyperkalemia?

- Check whether Hyperkalemia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Xenical:

Xenical (11,722 reports)

Hyperkalemia treatments and more:

Hyperkalemia (78,084 reports)

Browse all side effects of Xenical:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hyperkalemia:

Hyperkalemia (1,956 drugs)

Browse all the conditions that are associated with Hyperkalemia:

Hyperkalemia (2,937 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on orlistat (the active ingredients of Xenical) and Xenical (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.