Xermelo and Surgery - a phase IV clinical study of FDA data

Summary:

Surgery is reported as a side effect among people who take Xermelo (telotristat etiprate), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Sandostatin, and have Carcinoid syndrome.

The phase IV clinical study analyzes which people have Surgery when taking Xermelo. It is created by eHealthMe based on reports of 2,149 people who have side effects when taking Xermelo from the FDA, and is updated regularly.

What is Xermelo?

Xermelo has active ingredients of telotristat etiprate. eHealthMe is studying from 2,149 Xermelo users. Check the latest studies of Xermelo.

What is Surgery?

Surgery is found to be associated with 1,481 drugs and 1,245 conditions by eHealthMe. Check the latest studies of Surgery.

On Jul, 12, 2026

2,149 people reported to have side effects when taking Xermelo.
Among them, 27 people (1.26%) have Surgery.

Among these 27 people:

How long have people been on Xermelo when they have Surgery? *

What is the gender of people who have Surgery when taking Xermelo? *

female: 48.15 %
male: 51.85 %

What is the age of people who have Surgery when taking Xermelo? *

What are other drugs people take besides Xermelo? *

What are other side effects people have besides Surgery? *

Constipation: 10 people, 37.04%
Diarrhea: 6 people, 22.22%
Skin Blushing/flushing (a sudden reddening of the face, neck): 4 people, 14.81%
Post Procedural Complication: 3 people, 11.11%
High Blood Pressure: 3 people, 11.11%
Hospitalisation: 3 people, 11.11%
Dehydration (dryness resulting from the removal of water): 2 people, 7.41%
Drug Ineffective: 2 people, 7.41%
Dyspnea Exertional: 2 people, 7.41%
Nausea And Vomiting: 2 people, 7.41%

What are the existing conditions these people have? *

Carcinoid Syndrome (syndrome includes flushing and diarrhoea, and, less frequently, heart failure and bronchoconstriction): 16 people, 59.26%
Neuroendocrine Tumor: 4 people, 14.81%
Carcinoid Tumor Of The Small Bowel: 3 people, 11.11%
Carcinoid Tumor: 2 people, 7.41%
Neoplasm Malignant (cancer tumour): 1 person, 3.70%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 1 person, 3.70%
Drowsiness: 1 person, 3.70%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 1 person, 3.70%
Carcinoid Tumor Of The Duodenum: 1 person, 3.70%

* Approximation only. Some reports may have incomplete information.

Do you take Xermelo and have Surgery?

- Check whether Surgery is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Xermelo:

Xermelo (2,149 reports)

Surgery treatments and more:

Surgery (63,811 reports)

Browse all side effects of Xermelo:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Surgery:

Surgery (1,481 drugs)

Browse all the conditions that are associated with Surgery:

Surgery (1,245 conditions)

Related publications that referenced our studies

Briggs P, Hawrylack H, Mooney R, "Inhaled peppermint oil for postop nausea in patients undergoing cardiac surgery", Nursing, 2016 Jul .
Mariappan R, Prasad A, Venkatraghavan L, "An uncommon cause for severe hypophosphataemia after transsphenoidal pituitary surgery", Journal of Neuroanaesthesiology and Critical Care, 2014 May .
Briggs P, Hawrylack H, Mooney R, "Inhaled peppermint oil for postop nausea in patients undergoing cardiac surgery", Nursing, 2016 Jul .
Mariappan R, Prasad A, Venkatraghavan L, "An uncommon cause for severe hypophosphataemia after transsphenoidal pituitary surgery", Journal of Neuroanaesthesiology and Critical Care, 2014 May .

How the study uses the data?

The study uses data from the FDA. It is based on telotristat etiprate (the active ingredients of Xermelo) and Xermelo (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.