Xhance and Drug ineffective - a phase IV clinical study of FDA data

Summary:

Drug ineffective is reported as a side effect among people who take Xhance (fluticasone propionate), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Dupixent, and have Nasal polyps.

The phase IV clinical study analyzes which people have Drug ineffective when taking Xhance. It is created by eHealthMe based on reports of 2,005 people who have side effects when taking Xhance from the FDA, and is updated regularly.

What is Xhance?

Xhance has active ingredients of fluticasone propionate. eHealthMe is studying from 2,012 Xhance users. Check the latest studies of Xhance.

What is Drug ineffective?

Drug ineffective is found to be associated with 4,082 drugs and 5,192 conditions by eHealthMe. Check the latest studies of Drug ineffective.

On Aug, 01, 2026

2,005 people reported to have side effects when taking Xhance.
Among them, 86 people (4.29%) have Drug ineffective.

Among these 86 people:

How long have people been on Xhance when they have Drug ineffective? *

What is the gender of people who have Drug ineffective when taking Xhance? *

female: 39.53 %
male: 60.47 %

What is the age of people who have Drug ineffective when taking Xhance? *

What are other drugs people take besides Xhance? *

What are other side effects people have besides Drug ineffective? *

Nasal Congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels): 8 people, 9.30%
Nasal Polyps (masses that develop in the lining of the nose): 6 people, 6.98%
Smell - Impaired: 6 people, 6.98%
Nosebleed (bleeding from nose): 5 people, 5.81%
Sinusitis (inflammation of sinus): 5 people, 5.81%
Taste - Impaired: 3 people, 3.49%
Rhinorrhea (watery mucus discharge from the nose): 3 people, 3.49%
Sneezing: 3 people, 3.49%
Nausea And Vomiting: 2 people, 2.33%
Faeces Discolored: 2 people, 2.33%

What are the existing conditions these people have? *

Nasal Polyps (masses that develop in the lining of the nose): 41 people, 47.67%
Asthma: 8 people, 9.30%
Sinus Polyp (abnormal tissue growths that grow inside the nasal passages and sinuses): 1 person, 1.16%
Hypersensitivity: 1 person, 1.16%
High Blood Pressure: 1 person, 1.16%
Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters): 1 person, 1.16%
Dermatitis Atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder): 1 person, 1.16%
Birth Control: 1 person, 1.16%
Allergic Rhinitis: 1 person, 1.16%
Acne (skin problems that cause pimples): 1 person, 1.16%

* Approximation only. Some reports may have incomplete information.

Do you take Xhance and have Drug ineffective?

- Check whether Drug ineffective is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Xhance:

Xhance (2,012 reports)

Drug ineffective treatments and more:

Drug ineffective (1,349,510 reports)

Browse all side effects of Xhance:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Drug ineffective:

Drug ineffective (4,082 drugs)

Browse all the conditions that are associated with Drug ineffective:

Drug ineffective (5,192 conditions)

Related publications that referenced our studies

Lehrer, S., & Rheinstein, P. H. , "Alzheimer’s Disease and Intranasal Fluticasone Propionate in the FDA MedWatch Adverse Events Database", Journal of Alzheimer's disease reports, (Preprint), 1-5., 2018 Jan .
Lehrer, S., & Rheinstein, P. H. , "Alzheimer’s Disease and Intranasal Fluticasone Propionate in the FDA MedWatch Adverse Events Database", Journal of Alzheimer's disease reports, (Preprint), 1-5., 2018 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on fluticasone propionate (the active ingredients of Xhance) and Xhance (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.