Xhance and Fever - a phase IV clinical study of FDA data

Summary:

Fever is reported as a side effect among people who take Xhance (fluticasone propionate), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Dupixent, and have Nasal polyps.

The phase IV clinical study analyzes which people have Fever when taking Xhance. It is created by eHealthMe based on reports of 2,005 people who have side effects when taking Xhance from the FDA, and is updated regularly.

What is Xhance?

Xhance has active ingredients of fluticasone propionate. eHealthMe is studying from 2,012 Xhance users. Check the latest studies of Xhance.

What is Fever?

Fever is found to be associated with 3,494 drugs and 6,199 conditions by eHealthMe. Check the latest studies of Fever.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 04, 2026

2,005 people reported to have side effects when taking Xhance.
Among them, 26 people (1.3%) have Fever.

Among these 26 people:

How long have people been on Xhance when they have Fever? *

What is the gender of people who have Fever when taking Xhance? *

female: 65.38 %
male: 34.62 %

What is the age of people who have Fever when taking Xhance? *

What are other drugs people take besides Xhance? *

What are other side effects people have besides Fever? *

Cough: 15 people, 57.69%
Pneumonia: 7 people, 26.92%
Sinusitis (inflammation of sinus): 7 people, 26.92%
Headache (pain in head): 7 people, 26.92%
Oropharyngeal Pain: 6 people, 23.08%
Chills (felling of cold): 6 people, 23.08%
Thrombocytopenia (decrease of platelets in blood): 5 people, 19.23%
Infusion Related Reaction: 5 people, 19.23%
Adenovirus Infection: 5 people, 19.23%
Swallowing Difficulty: 4 people, 15.38%

What are the existing conditions these people have? *

Nasal Polyps (masses that develop in the lining of the nose): 14 people, 53.85%
Immunodeficiency Common Variable: 8 people, 30.77%
Asthma: 4 people, 15.38%
Multiple Allergies (allergy to multiple agents): 2 people, 7.69%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 7.69%
Cystic Fibrosis (disease of the secretary glands): 1 person, 3.85%
Eosinophilia (eosinophil count in the peripheral blood exceeds): 1 person, 3.85%
Hiv Infection: 1 person, 3.85%
Smell - Impaired: 1 person, 3.85%
Sinus Polyp Degeneration (degeneration of abnormal tissue growths that grow inside the nasal passages and sinuses): 1 person, 3.85%

* Approximation only. Some reports may have incomplete information.

Do you take Xhance and have Fever?

- Check whether Fever is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Xhance:

Xhance (2,012 reports)

Fever treatments and more:

Fever (498,666 reports)

Browse all side effects of Xhance:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Fever:

Fever (3,494 drugs)

Browse all the conditions that are associated with Fever:

Fever (6,199 conditions)

Related publications that referenced our studies

Lehrer, S., & Rheinstein, P. H. , "Alzheimer’s Disease and Intranasal Fluticasone Propionate in the FDA MedWatch Adverse Events Database", Journal of Alzheimer's disease reports, (Preprint), 1-5., 2018 Jan .
Schiller D, Maieron A, Sch?fl R, Donnerer J, "Drug fever due to a single dose of pantoprazole", Pharmacology, 2015 Jan .
Lehrer, S., & Rheinstein, P. H. , "Alzheimer’s Disease and Intranasal Fluticasone Propionate in the FDA MedWatch Adverse Events Database", Journal of Alzheimer's disease reports, (Preprint), 1-5., 2018 Jan .
Schiller D, Maieron A, Sch?fl R, Donnerer J, "Drug fever due to a single dose of pantoprazole", Pharmacology, 2015 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on fluticasone propionate (the active ingredients of Xhance) and Xhance (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.