Xiaflex and Perforated eardrum - a phase IV clinical study of FDA data

Summary:

We study 7,526 people who take Xiaflex (collagenase clostridium histolyticum) or have Perforated eardrum. No report of Perforated eardrum is found in people who take Xiaflex.

The phase IV clinical study is created by eHealthMe based on reports from the FDA, and is updated regularly.

What is Xiaflex?

Xiaflex has active ingredients of collagenase clostridium histolyticum. eHealthMe is studying from 5,177 Xiaflex users. Check the latest studies of Xiaflex.

What is Perforated Eardrum?

Perforated eardrum (hole or tear in the eardrum) is found to be associated with 667 drugs and 806 conditions by eHealthMe. Check the latest studies of Perforated eardrum.

On Jun, 18, 2026

No report is found.

Do you take Xiaflex and have Perforated eardrum?

- Check whether Perforated eardrum is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Xiaflex:

Xiaflex (5,177 reports)

Perforated eardrum treatments and more:

Perforated eardrum (2,349 reports)

How severe was Perforated eardrum and when was it recovered:

Perforated eardrum in Xiaflex

Expand to all the drugs that have ingredients of collagenase clostridium histolyticum:

Perforated eardrum and drugs with ingredients of collagenase clostridium histolyticum

Browse all side effects of Xiaflex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Perforated eardrum:

Perforated eardrum

Browse all the conditions that are associated with Perforated eardrum:

Perforated eardrum

How the study uses the data?

The study uses data from the FDA. It is based on collagenase clostridium histolyticum (the active ingredients of Xiaflex) and Xiaflex (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.