Xiaflex and Peripheral swelling - a phase IV clinical study of FDA data
Summary:
Peripheral swelling is found among people who take Xiaflex, especially for people who are male, 60+ old, have been taking the drug for < 1 month.
The phase IV clinical study analyzes which people take Xiaflex and have Peripheral swelling. It is created by eHealthMe based on reports of 3,702 people who have side effects when taking Xiaflex from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
On May, 31, 2022
3,702 people reported to have side effects when taking Xiaflex.
Among them, 123 people (3.32%) have Peripheral swelling.
What is Xiaflex?
Xiaflex has active ingredients of collagenase clostridium histolyticum. eHealthMe is studying from 3,704 Xiaflex users for its effectiveness, alternative drugs and more.
What is Peripheral swelling?
Peripheral swelling is found to be associated with 1,943 drugs and 1,545 conditions by eHealthMe.
Number of Xiaflex and Peripheral swelling reports submitted per year:
Time on Xiaflex when people have Peripheral swelling *:
Gender of people who have Peripheral swelling when taking Xiaflex*:
Age of people who have Peripheral swelling when taking Xiaflex *:
Common drugs people take besides Xiaflex *:
Common side effects people have besides Peripheral swelling *:
Common conditions people have *:
* Approximation only. Some reports may have incomplete information.
Do you take Xiaflex and have Peripheral swelling?
Check whether Peripheral swelling is associated with a drug or a conditionHow to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related studies
How severe was Peripheral swelling and when was it recovered:
Expand to all the drugs that have ingredients of collagenase clostridium histolyticum:
Alternative drugs to, pros and cons of Xiaflex:
- Xiaflex (3,704 reports)
Common Xiaflex side effects:
- Curvature of the penis: 125 reports
- Cuts and puncture wounds: 116 reports
- Drug ineffective: 899 reports
- Dupuytren's contracture (thickening of the fibrous tissue layer underneath the skin of the palm and fingers): 137 reports
- Fracture of penis (rupture of one or both of covering): 362 reports
- Head injury: 453 reports
- Injection site bruising: 165 reports
- Injection site pain: 293 reports
- Injection site swelling: 190 reports
- Pain: 280 reports
- Pain in extremity: 154 reports
- Penile haematoma (localized collection of blood outside the blood vessels on penis): 183 reports
- Penile pain: 247 reports
- Penile swelling: 394 reports
- Peripheral swelling: 123 reports
- Swelling: 324 reports
Browse all side effects of Xiaflex:
a b c d e f g h i j k l m n o p q r s t u v w x y zPeripheral swelling treatments and more:
- Peripheral swelling (117,150 reports)
COVID vaccines that are related to Peripheral swelling:
- Peripheral swelling in Moderna COVID Vaccine
- Peripheral swelling in Pfizer BioNTech Covid Vaccine
- Peripheral swelling in Johnson and Johnson Covid Vaccine
Common drugs associated with Peripheral swelling:
- Abilify: 367 reports
- Acetylsalicylic acid: 988 reports
- Actemra: 8,213 reports
- Acth: 137 reports
- Acthar: 137 reports
- Actonel: 388 reports
- Actos: 205 reports
- Adalat: 104 reports
- Adcirca: 1,506 reports
- Adderall: 378 reports
- Adempas: 1,507 reports
- Advair hfa: 1,064 reports
- Advil: 600 reports
- Afinitor: 898 reports
- Aimovig: 115 reports
- Albuterol: 1,099 reports
- Albuterol sulfate: 347 reports
- Aldactone: 390 reports
- Alendronate sodium: 872 reports
- Alendronic acid: 454 reports
- Aleve: 663 reports
- Allegra: 386 reports
- Allopurinol: 1,737 reports
- Alprazolam: 874 reports
- Altace: 186 reports
- Alvesco: 185 reports
- Amaryl: 110 reports
- Ambien: 609 reports
- Amitiza: 124 reports
- Amitriptyline hydrochloride: 164 reports
- Amlodipine: 5,283 reports
- Amlodipine besylate: 822 reports
- Amoxicillin: 714 reports
- Ampyra: 679 reports
- Anastrozole: 207 reports
- Androgel: 134 reports
- Anoro ellipta: 164 reports
- Apixaban: 422 reports
- Aranesp: 191 reports
- Arava: 4,326 reports
- Aricept: 103 reports
- Aripiprazole: 128 reports
- Armour thyroid: 159 reports
- Aromasin: 144 reports
- Arthrotec: 222 reports
- Asa: 789 reports
- Asacol: 196 reports
- Aspirin: 6,116 reports
- Atacand: 222 reports
- Atenolol: 1,605 reports
- Ativan: 809 reports
- Atorvastatin calcium: 699 reports
- Atrovent: 309 reports
- Aubagio: 522 reports
- Augmentin: 149 reports
- Avandia: 146 reports
- Avapro: 219 reports
- Avastin: 210 reports
- Avelox: 124 reports
- Avonex: 527 reports
- Azathioprine: 635 reports
- Azelastine: 133 reports
- Baby aspirin: 591 reports
- Baclofen: 1,096 reports
- Bactrim: 517 reports
- Bactrim ds: 118 reports
- Benadryl: 1,609 reports
- Benicar: 249 reports
- Benlysta: 220 reports
- Benzonatate: 190 reports
- Bicalutamide: 102 reports
- Biotin: 620 reports
- Bisacodyl: 120 reports
- Bisoprolol fumarate: 271 reports
- Boniva: 150 reports
- Botox: 131 reports
- Breo ellipta: 310 reports
- Brilinta: 158 reports
- Budesonide: 291 reports
- Bumetanide: 328 reports
- Bumex: 173 reports
- Butrans: 116 reports
- Bydureon: 129 reports
- Bystolic: 240 reports
- Cabergoline: 118 reports
- Cabometyx: 259 reports
- Calcitriol: 215 reports
- Calcium: 2,573 reports
- Calcium citrate: 194 reports
- Cannabis: 181 reports
- Captopril: 186 reports
- Carafate: 121 reports
- Carbamazepine: 147 reports
- Carboplatin: 154 reports
- Cardizem: 190 reports
- Cartia xt: 122 reports
- Carvedilol: 1,301 reports
- Cefdinir: 110 reports
- Celebrex: 2,829 reports
- Celecoxib: 432 reports
- Celexa: 298 reports
- Cellcept: 216 reports
- Centrum: 505 reports
- Centrum silver: 340 reports
- Cephalexin: 327 reports
- Cetirizine hydrochloride: 578 reports
- Chantix: 118 reports
- Chlorhexidine gluconate: 396 reports
- Chlorthalidone: 230 reports
- Cialis: 118 reports
- Cimzia: 1,704 reports
- Cipro: 252 reports
- Citalopram hydrobromide: 160 reports
- Clarithromycin: 190 reports
- Claritin: 537 reports
- Clexane: 107 reports
- Clonazepam: 1,195 reports
- Clonidine: 651 reports
- Clopidogrel: 876 reports
- Codeine: 1,410 reports
- Coenzyme q10: 678 reports
- Colace: 488 reports
- Colchicine: 408 reports
- Colecalciferol: 330 reports
- Compazine: 165 reports
- Copaxone: 315 reports
- Coq: 168 reports
- Coq10: 160 reports
- Coreg: 459 reports
- Cosentyx: 2,786 reports
- Coumadin: 1,206 reports
- Cozaar: 314 reports
- Creon: 184 reports
- Crestor: 1,237 reports
- Cymbalta: 1,302 reports
- Decadron: 295 reports
- Depakote: 241 reports
- Depo-medrol: 360 reports
- Desogestrel and ethinyl estradiol: 132 reports
- Detrol: 125 reports
- Dexamethasone: 249 reports
- Dexilant: 668 reports
- Diazepam: 633 reports
- Diclofenac: 756 reports
- Diclofenac sodium: 305 reports
- Digoxin: 643 reports
- Dilaudid: 730 reports
- Diovan: 609 reports
- Diovan hct: 112 reports
- Diphenhydramine hydrochloride: 508 reports
- Docetaxel: 248 reports
- Donepezil: 212 reports
- Doxycycline: 750 reports
- Doxycycline hyclate: 174 reports
- Dulcolax: 155 reports
- Dupixent: 587 reports
- Effexor: 495 reports
- Elavil: 164 reports
- Eligard: 113 reports
- Eliquis: 2,216 reports
- Enablex: 156 reports
- Enbrel: 12,196 reports
- Entresto: 1,359 reports
- Entyvio: 191 reports
- Epipen: 206 reports
- Eplerenone: 136 reports
- Ergocalciferol: 726 reports
- Esbriet: 299 reports
- Escitalopram: 519 reports
- Esomeprazole magnesium: 176 reports
- Estrace: 160 reports
- Evista: 151 reports
- Exemestane: 171 reports
- Exforge: 154 reports
- Exjade: 182 reports
- Extraneal: 240 reports
- Ezetimibe: 183 reports
- Famotidine: 480 reports
- Faslodex: 197 reports
- Felodipine: 106 reports
- Femara: 125 reports
- Fenofibrate: 383 reports
- Fentanyl: 299 reports
- Ferrous fumarate: 182 reports
- Finasteride: 403 reports
- Fish oil: 1,672 reports
- Flax: 174 reports
- Flaxseed: 160 reports
- Flexeril: 452 reports
- Flolan: 124 reports
- Flomax: 458 reports
- Flonase: 721 reports
- Flovent: 408 reports
- Fluconazole: 300 reports
- Fluorouracil: 165 reports
- Fluoxetine: 487 reports
- Fluticasone propionate: 295 reports
- Forteo: 1,037 reports
- Fosamax: 710 reports
- Fragmin: 101 reports
- Furosemide: 5,114 reports
- Gabapentin: 4,298 reports
- Gemfibrozil: 122 reports
- Genotropin: 123 reports
- Gilenya: 647 reports
- Gleevec: 314 reports
- Gliclazide: 341 reports
- Glimepiride: 437 reports
- Glipizide: 628 reports
- Glucophage: 283 reports
- Glucosamine: 272 reports
- Glyburide: 184 reports
- Gravol: 332 reports
- Harvoni: 117 reports
- Hctz: 508 reports
- Heparin: 326 reports
- Herceptin: 247 reports
- Humalog: 774 reports
- Humira: 11,659 reports
- Hydramine: 1,571 reports
- Hydrea: 101 reports
- Hydrochlorothiazide: 2,130 reports
- Hydrocodone bitartrate and acetaminophen: 301 reports
- Hydromorphone hydrochloride: 123 reports
- Hydroxychloroquine sulfate: 2,364 reports
- Hydroxyurea: 157 reports
- Hydroxyzine: 605 reports
- Hyzaar: 102 reports
- Ibrance: 905 reports
- Ibu: 2,938 reports
- Ibuprofen: 2,925 reports
- Imbruvica: 1,342 reports
- Imdur: 102 reports
- Imodium: 476 reports
- Imuran: 375 reports
- Indapamide: 245 reports
- Indomethacin: 132 reports
- Inflectra: 433 reports
- Insulin: 867 reports
- Invokana: 159 reports
- Ipratropium bromide: 123 reports
- Irbesartan: 403 reports
- Isoniazid: 116 reports
- Isosorbide mononitrate: 208 reports
- Jakafi: 889 reports
- Janumet: 198 reports
- Januvia: 605 reports
- Jardiance: 196 reports
- Kadcyla: 125 reports
- Kadian: 174 reports
- Keflex: 153 reports
- Kenalog: 195 reports
- Keppra: 267 reports
- Ketoconazole: 163 reports
- Ketoprofen: 154 reports
- Kevzara: 198 reports
- Keytruda: 141 reports
- Kineret: 198 reports
- Klonopin: 439 reports
- Klor-con: 444 reports
- Korlym: 213 reports
- Kyprolis: 123 reports
- Lactulose: 259 reports
- Lamictal: 218 reports
- Lamisil: 104 reports
- Lamotrigine: 228 reports
- Lansoprazole: 676 reports
- Lantus: 1,292 reports
- Lantus solostar: 195 reports
- Lasix: 3,565 reports
- Latanoprost: 272 reports
- Leflunomide: 3,067 reports
- Lemtrada: 153 reports
- Lenvima: 205 reports
- Letairis: 2,362 reports
- Letrozole: 572 reports
- Levaquin: 343 reports
- Levetiracetam: 180 reports
- Levothyroxine sodium: 628 reports
- Levoxyl: 139 reports
- Lexapro: 542 reports
- Linzess: 196 reports
- Lipitor: 1,793 reports
- Lisinopril: 3,369 reports
- Lomotil: 218 reports
- Lopressor: 200 reports
- Loratadine: 492 reports
- Loraz: 1,027 reports
- Lorazepam: 1,154 reports
- Lortab: 132 reports
- Losartan: 3,051 reports
- Losartan potassium: 616 reports
- Lovastatin: 371 reports
- Lovenox: 257 reports
- Lupron: 397 reports
- Lupron depot: 176 reports
- Lutein: 116 reports
- Lyrica: 4,574 reports
- Magnesium: 1,278 reports
- Makena: 247 reports
- Mayzent: 142 reports
- Meclizine: 353 reports
- Medrol: 165 reports
- Mefenamic acid: 163 reports
- Mekinist: 201 reports
- Melatonin: 520 reports
- Meloxicam: 1,499 reports
- Metformin: 4,014 reports
- Metformin hydrochloride: 281 reports
- Methocarbamol: 208 reports
- Methotrexate: 12,505 reports
- Methotrexate sodium: 2,403 reports
- Methylprednisolone sodium succinate: 194 reports
- Metolazone: 323 reports
- Metoprolol succinate: 653 reports
- Metoprolol tartrate: 726 reports
- Metronidazole: 313 reports
- Micardis: 198 reports
- Minoxidil: 118 reports
- Miralax: 670 reports
- Mirapex: 208 reports
- Mirena: 191 reports
- Mirtazapine: 469 reports
- Mobic: 217 reports
- Modafinil: 167 reports
- Montelukast sodium: 227 reports
- Morphine: 1,582 reports
- Morphine sulfate: 440 reports
- Motrin: 435 reports
- Ms contin: 119 reports
- Mucinex: 297 reports
- Multivitamin: 1,190 reports
- Myrbetriq: 424 reports
- Nabumetone: 102 reports
- Naprosyn: 469 reports
- Naproxen: 523 reports
- Nasonex: 314 reports
- Neulasta: 148 reports
- Neurontin: 756 reports
- Nexavar: 242 reports
- Nexium: 1,240 reports
- Nexplanon: 228 reports
- Nifedipine: 602 reports
- Ninlaro: 334 reports
- Nitroglycerin: 311 reports
- Nitrostat: 184 reports
- Norco: 809 reports
- Norflex: 264 reports
- Northera: 153 reports
- Norvasc: 1,188 reports
- Novolog: 630 reports
- Novorapid: 197 reports
- Nucala: 155 reports
- Nuplazid: 1,061 reports
- Nuvaring: 104 reports
- Nuvigil: 181 reports
- Ocrevus: 284 reports
- Ofev: 212 reports
- Olanzapine: 260 reports
- Omega 3: 240 reports
- Omeprazole: 4,543 reports
- Omnaris: 274 reports
- Ondansetron: 859 reports
- Opdivo: 184 reports
- Opsumit: 2,710 reports
- Orencia: 4,816 reports
- Otezla: 1,078 reports
- Oxybutynin: 305 reports
- Oxybutynin chloride: 134 reports
- Oxycodone: 1,936 reports
- Oxycodone and acetaminophen: 210 reports
- Oxycontin: 476 reports
- Paclitaxel: 174 reports
- Pantoprazole: 4,137 reports
- Pantoprazole sodium: 1,028 reports
- Paracetamol: 1,234 reports
- Paxil: 274 reports
- Pegasys: 142 reports
- Pepcid: 359 reports
- Percocet: 760 reports
- Phenergan: 183 reports
- Pioglitazone: 145 reports
- Plaquenil: 5,402 reports
- Plavix: 871 reports
- Pomalyst: 905 reports
- Potassium: 1,354 reports
- Pradaxa: 319 reports
- Praluent: 220 reports
- Pravachol: 130 reports
- Pravastatin sodium: 201 reports
- Prednisolone: 1,220 reports
- Prednisone: 10,976 reports
- Pregabalin: 759 reports
- Premarin: 374 reports
- Prevacid: 382 reports
- Prilosec: 985 reports
- Prinivil: 143 reports
- Proair hfa: 570 reports
- Probiotic: 436 reports
- Procardia: 104 reports
- Progesterone: 147 reports
- Prograf: 147 reports
- Prolia: 931 reports
- Promacta: 118 reports
- Promethazine: 294 reports
- Protonix: 794 reports
- Proventil: 199 reports
- Provigil: 140 reports
- Prozac: 387 reports
- Pulmicort: 251 reports
- Q10: 736 reports
- Quetiapine fumarate: 116 reports
- Quinapril: 110 reports
- Qvar: 151 reports
- Rabeprazole: 327 reports
- Ramipril: 1,339 reports
- Ranexa: 121 reports
- Ranitidine: 1,245 reports
- Rapamune: 147 reports
- Rebif: 138 reports
- Reclast: 113 reports
- Reglan: 109 reports
- Remeron: 127 reports
- Remicade: 3,045 reports
- Remodulin: 893 reports
- Repatha: 765 reports
- Requip: 155 reports
- Restasis: 394 reports
- Revatio: 823 reports
- Revlimid: 3,132 reports
- Ribavirin: 197 reports
- Risedronate sodium: 219 reports
- Risperidone: 146 reports
- Ritalin: 141 reports
- Rituxan: 2,449 reports
- Rivaroxaban: 157 reports
- Rogaine: 158 reports
- Rosuvastatin calcium: 587 reports
- Rytary: 133 reports
- Sandostatin: 1,223 reports
- Sandostatin lar: 1,115 reports
- Senna: 411 reports
- Sensipar: 114 reports
- Septra: 167 reports
- Seroquel: 391 reports
- Sertraline: 918 reports
- Sildenafil citrate: 436 reports
- Simponi: 2,650 reports
- Simvastatin: 2,278 reports
- Sinemet: 291 reports
- Singulair: 1,314 reports
- Sodium bicarbonate: 166 reports
- Soliris: 554 reports
- Solu-medrol: 286 reports
- Spiriva: 1,341 reports
- Spironolactone: 1,573 reports
- Sprycel: 241 reports
- Stelara: 620 reports
- Stivarga: 152 reports
- Suboxone: 105 reports
- Sucralfate: 161 reports
- Sulfamethoxazole: 380 reports
- Sulfamethoxazole and trimethoprim: 349 reports
- Sulfasalazine: 3,898 reports
- Sutent: 596 reports
- Symbicort: 1,304 reports
- Synthroid: 3,047 reports
- Tacrolimus: 255 reports
- Tadalafil: 383 reports
- Tafinlar: 186 reports
- Taltz: 143 reports
- Tamsulosin: 933 reports
- Tarceva: 148 reports
- Tasigna: 291 reports
- Taxol: 124 reports
- Taxotere: 209 reports
- Tecfidera: 727 reports
- Tegretol: 142 reports
- Temaz: 298 reports
- Thalomid: 152 reports
- Theophylline: 107 reports
- Thiamine: 110 reports
- Topamax: 281 reports
- Topiramate: 300 reports
- Torsemide: 370 reports
- Tracleer: 525 reports
- Tradjenta: 149 reports
- Tramadol: 2,396 reports
- Tramadol hydrochloride: 283 reports
- Trazodone hydrochloride: 146 reports
- Tresiba: 303 reports
- Triamcinolone: 192 reports
- Triamcinolone acetonide: 171 reports
- Trulicity: 248 reports
- Turmeric: 218 reports
- Tylenol: 3,681 reports
- Tysabri: 463 reports
- Tyvaso: 570 reports
- Uloric: 262 reports
- Ultram: 224 reports
- Urispas: 191 reports
- Vagifem: 331 reports
- Valacyclovir: 286 reports
- Valium: 291 reports
- Valsartan: 829 reports
- Valtrex: 279 reports
- Velcade: 518 reports
- Veletri: 582 reports
- Veltassa: 179 reports
- Venclexta: 179 reports
- Venlafaxine hydrochloride: 162 reports
- Venofer: 134 reports
- Ventavis: 165 reports
- Ventolin: 950 reports
- Ventolin hfa: 359 reports
- Vesicare: 257 reports
- Viagra: 167 reports
- Vicodin: 293 reports
- Victoza: 248 reports
- Viekira pak: 169 reports
- Vimovo: 200 reports
- Vioxx: 176 reports
- Vitamin b: 257 reports
- Vitamin b12: 1,912 reports
- Vitamin b6: 235 reports
- Vitamin c: 1,736 reports
- Vitamin d: 5,528 reports
- Vitamin d3: 2,004 reports
- Vitamin e: 449 reports
- Vitamins: 604 reports
- Vivitrol: 111 reports
- Voltaren: 759 reports
- Votrient: 161 reports
- Vyvanse: 116 reports
- Warfarin sodium: 273 reports
- Wellbutrin: 521 reports
- Xalkori: 276 reports
- Xanax: 1,072 reports
- Xarelto: 1,944 reports
- Xeljanz: 7,195 reports
- Xeljanz xr: 2,155 reports
- Xeloda: 378 reports
- Xgeva: 291 reports
- Xiaflex: 123 reports
- Xifaxan: 150 reports
- Xolair: 1,330 reports
- Xtandi: 1,358 reports
- Xyrem: 568 reports
- Yaz: 104 reports
- Zanaflex: 160 reports
- Zantac: 684 reports
- Zejula: 253 reports
- Zelboraf: 130 reports
- Zetia: 280 reports
- Zide: 2,140 reports
- Zithromax: 120 reports
- Zocor: 382 reports
- Zofran: 840 reports
- Zoledronic acid: 286 reports
- Zoloft: 591 reports
- Zolpidem: 528 reports
- Zolpidem tartrate: 159 reports
- Zometa: 471 reports
- Zopiclone: 1,010 reports
- Zyloprim: 117 reports
- Zyprexa: 122 reports
- Zyrtec: 820 reports
- Zytiga: 322 reports
All the drugs that are associated with Peripheral swelling:
- Peripheral swelling (1,943 drugs)
Common conditions associated with Peripheral swelling:
- Abdominal discomfort: 195 reports
- Acid reflux: 1,341 reports
- Acne: 113 reports
- Acromegaly: 480 reports
- Acupuncture and pain: 1,422 reports
- Acute myeloid leukaemia: 104 reports
- Adenocarcinoma of renal cells: 631 reports
- A-fib: 885 reports
- Anaemia: 316 reports
- Anasarca: 291 reports
- Ankylosing spondylitis: 1,544 reports
- Anticoagulant therapy: 544 reports
- Antidepressant therapy: 1,618 reports
- Anxiety: 1,363 reports
- Apprehension: 1,257 reports
- Arrhythmias: 205 reports
- Arthralgia: 691 reports
- Arthritis: 1,211 reports
- Asthma: 2,431 reports
- Atrial fibrillation: 917 reports
- Atrial fibrillation/flutter: 917 reports
- Atrial flutter: 885 reports
- Attention deficit hyperactivity disorder: 120 reports
- Back pain: 692 reports
- Bipolar disorder: 242 reports
- Birth control: 594 reports
- Blood cholesterol abnormal: 2,767 reports
- Blood cholesterol increased: 2,767 reports
- Blood clot in the legs: 465 reports
- Blood pressure abnormal: 1,147 reports
- Blood pressure inadequately controlled: 945 reports
- Blood pressure increased: 5,334 reports
- Blood pressure management: 945 reports
- Blood triglycerides abnormal: 2,974 reports
- Blood triglycerides increased: 2,767 reports
- Breast cancer: 879 reports
- Breast cancer metastatic: 678 reports
- Breathing difficulty: 314 reports
- Burkitt lymphoma: 109 reports
- Cancer - breast: 955 reports
- Can't sleep: 631 reports
- Carcinoid syndrome: 139 reports
- Carcinoid tumor: 252 reports
- Cardiac disorder: 762 reports
- Cardiac failure congestive: 209 reports
- Cataplexy: 259 reports
- Chest pain: 196 reports
- Chronic kidney disease: 225 reports
- Chronic lymphocytic leukaemia: 1,075 reports
- Chronic myeloid leukaemia: 761 reports
- Chronic obstructive pulmonary disease: 819 reports
- Ckd: 221 reports
- Colitis ulcerative: 780 reports
- Community-acquired pneumonia: 203 reports
- Constipation: 453 reports
- Contraception: 618 reports
- Copd: 785 reports
- Coronary heart disease: 123 reports
- Crohn's disease: 1,886 reports
- Crohns disease: 2,308 reports
- Cystic fibrosis: 119 reports
- Cystitis: 424 reports
- Deep vein thrombosis: 465 reports
- Deep venous thrombosis: 436 reports
- Depression: 1,541 reports
- Diabetes: 2,068 reports
- Diabetes mellitus: 2,280 reports
- Diabetes mellitus management: 2,265 reports
- Diabetes mellitus non-insulin-dependent: 368 reports
- Diabetes - type 2: 1,549 reports
- Diabetic neuropathy: 342 reports
- Diarrhea: 277 reports
- Diarrhea aggravated: 304 reports
- Diffuse large b-cell lymphoma: 184 reports
- Diuretic therapy: 335 reports
- Dizziness: 119 reports
- Drug dependence: 103 reports
- Dry eyes: 137 reports
- Dupuytren's contracture: 122 reports
- Dvt: 436 reports
- Dyslipidemia: 2,767 reports
- Dyspepsia: 407 reports
- Eczema: 119 reports
- Edema: 312 reports
- Epilepsy: 193 reports
- Feeling uptight: 1,362 reports
- Fibromyalgia: 1,110 reports
- Fluid retention: 365 reports
- Gait disturbance: 290 reports
- Gastric disorder: 299 reports
- Gastric ulcer: 121 reports
- Gastroesophageal reflux disease: 1,439 reports
- Gastrointestinal stromal tumor: 257 reports
- Gastrooesophageal reflux disease: 1,341 reports
- Gerd: 1,341 reports
- Glaucoma: 176 reports
- Gout: 379 reports
- Growth hormone deficiency: 128 reports
- Haemolytic uraemic syndrome: 136 reports
- Hairloss: 181 reports
- Hair loss: 181 reports
- Hbp: 5,334 reports
- Headache: 440 reports
- Heartburn: 1,341 reports
- Heart disease: 109 reports
- Hepatitis c: 490 reports
- Hepatocellular carcinoma: 162 reports
- Hereditary angioedema: 132 reports
- Herpes zoster: 115 reports
- Hidradenitis: 106 reports
- High blood cholesterol: 2,767 reports
- High blood cholesterol and triglycerides: 2,974 reports
- High blood pressure: 5,334 reports
- High cholesterol: 2,767 reports
- Hiv infection: 166 reports
- Hormone replacement therapy: 193 reports
- Hypercholesterolaemia: 2,767 reports
- Hypercholesterolemia: 2,767 reports
- Hyperlipidemia: 2,767 reports
- Hypernephroma: 690 reports
- Hypersensitivity: 654 reports
- Hypertension: 5,788 reports
- Hypertonic bladder: 161 reports
- Hypothyroidism: 967 reports
- Idiopathic myelofibrosis: 622 reports
- Idiopathic pulmonary fibrosis: 496 reports
- Ileitis: 1,669 reports
- Ileitis aggravated: 1,886 reports
- Ill-defined disorder: 110 reports
- Immunodeficiency common variable: 225 reports
- Indigestion: 447 reports
- Inflammation: 241 reports
- Inflammatory bowel disease - crohn's disease: 1,669 reports
- Inflammatory bowel disease - ulcerative colitis: 780 reports
- Insomnia: 595 reports
- Irritable bowel syndrome: 121 reports
- Joint pain: 628 reports
- Joint swelling: 102 reports
- Juvenile rheumatoid arthritis: 239 reports
- Kidney transplant: 154 reports
- Lipid profile: 1,060 reports
- Lipid test: 2,974 reports
- Liver cancer: 162 reports
- Lower respiratory tract infection: 134 reports
- Lung neoplasm malignant: 470 reports
- Lupus: 348 reports
- Malignant melanoma: 247 reports
- Mantle cell lymphoma: 145 reports
- Metastatic renal cell carcinoma: 187 reports
- Migraine: 507 reports
- Migraines: 551 reports
- Mineral supplementation: 199 reports
- Ms: 3,381 reports
- Multiple myeloma: 4,551 reports
- Multiple sclerosis: 3,381 reports
- Muscle relaxant therapy: 146 reports
- Muscle spasms: 489 reports
- Myelofibrosis: 622 reports
- Myeloma - multiple: 4,551 reports
- Narcolepsy: 476 reports
- Nasopharyngitis: 114 reports
- Nausea: 540 reports
- Neoplasm malignant: 251 reports
- Nerve injury: 194 reports
- Neuralgia: 713 reports
- Neuroendocrine tumor: 574 reports
- Neuroendocrine tumour: 574 reports
- Neuropathy peripheral: 1,144 reports
- Niddm: 1,549 reports
- Nocturnal myoclonus: 473 reports
- Non-hodgkin's lymphoma: 156 reports
- Oedema: 157 reports
- Osteoarthritis: 363 reports
- Osteopenia: 155 reports
- Osteoporosis: 1,872 reports
- Osteoporosis postmenopausal: 296 reports
- Osteoporosis post-menopausal: 296 reports
- Pain: 4,260 reports
- Pain in extremity: 511 reports
- Pain management: 4,244 reports
- Parkinsons: 104 reports
- Parkinson's disease: 871 reports
- Paroxysmal nocturnal haemoglobinuria: 190 reports
- Peripheral swelling: 146 reports
- Plasma cell myeloma: 5,904 reports
- Pneumonia: 205 reports
- Polycythaemia vera: 304 reports
- Pregnancy: 594 reports
- Preventive health care: 352 reports
- Primary myelofibrosis: 622 reports
- Primary pulmonary hypertension: 5,148 reports
- Prostate cancer: 1,435 reports
- Prostate cancer metastatic: 152 reports
- Psoriasis: 3,330 reports
- Psoriatic arthropathy: 4,232 reports
- Pulmonary arterial hypertension: 5,148 reports
- Pulmonary embolism: 216 reports
- Pulmonary hypertension: 1,899 reports
- Quincke's disease: 132 reports
- Quit smoking: 137 reports
- Ra: 18,804 reports
- Rash: 292 reports
- Rash generalised: 238 reports
- Relapsing-remitting multiple sclerosis: 370 reports
- Renal cell carcinoma: 792 reports
- Restless leg syndrome: 362 reports
- Rheumatoid arthritis: 18,804 reports
- Schizophrenia: 163 reports
- Seasonal allergy: 158 reports
- Seizures: 303 reports
- Shingles: 115 reports
- Sinus infection: 195 reports
- Skin rash: 238 reports
- Sleep disorder: 783 reports
- Sleep disorder therapy: 783 reports
- Smoker: 137 reports
- Spondylitis: 1,076 reports
- Stable angina: 102 reports
- Stress: 1,566 reports
- Stress and anxiety: 1,257 reports
- Stroke: 666 reports
- Supplementation therapy: 415 reports
- Swelling: 292 reports
- Systemic lupus erythematosus: 348 reports
- Tachycardia aggravated: 188 reports
- Thrombosis: 599 reports
- Thyroid diseases: 695 reports
- Thyroid disorder: 695 reports
- Type 1 diabetes: 140 reports
- Type 1 diabetes mellitus: 140 reports
- Type 2 diabetes: 1,549 reports
- Type 2 diabetes mellitus: 1,549 reports
- Ulcerative colitis: 780 reports
- Urinary tract infection: 425 reports
- Urticaria: 170 reports
- Uti: 499 reports
- Vitamin supplementation: 489 reports
- Waldenstrom's macroglobulinaemia: 141 reports
- Water retention: 365 reports
All the conditions that are associated with Peripheral swelling:
- Peripheral swelling (1,545 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on collagenase clostridium histolyticum (the active ingredients of Xiaflex) and Xiaflex (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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