Xifaxan and Nightmares - a phase IV clinical study of FDA data

Summary:

Nightmares is reported as a side effect among people who take Xifaxan (rifaximin), especially for people who are female, 60+ old, have been taking the drug for 5 - 10 years also take Lexapro, and have Cushing's syndrome.

The phase IV clinical study analyzes which people have Nightmares when taking Xifaxan. It is created by eHealthMe based on reports of 16,409 people who have side effects when taking Xifaxan from the FDA, and is updated regularly.

What is Xifaxan?

Xifaxan has active ingredients of rifaximin. It is often used in irritable bowel syndrome. eHealthMe is studying from 16,609 Xifaxan users. Check the latest studies of Xifaxan.

What is Nightmares?

Nightmares (unpleasant dreams) is found to be associated with 1,337 drugs and 1,912 conditions by eHealthMe. Check the latest studies of Nightmares.

On Jul, 09, 2026

16,409 people reported to have side effects when taking Xifaxan.
Among them, 14 people (0.09%) have Nightmares.

Among these 14 people:

How long have people been on Xifaxan when they have Nightmares? *

What is the gender of people who have Nightmares when taking Xifaxan? *

female: 58.33 %
male: 41.67 %

What is the age of people who have Nightmares when taking Xifaxan? *

What are other drugs people take besides Xifaxan? *

What are other side effects people have besides Nightmares? *

Nausea (feeling of having an urge to vomit): 6 people, 42.86%
Fatigue (feeling of tiredness): 5 people, 35.71%
Memory Loss: 4 people, 28.57%
Abdominal Pain Upper: 4 people, 28.57%
Drowsiness: 4 people, 28.57%
Stress And Anxiety: 4 people, 28.57%
Dizziness: 4 people, 28.57%
Weight Decreased: 3 people, 21.43%
Confusion: 3 people, 21.43%
Confusional State: 3 people, 21.43%

What are the existing conditions these people have? *

Sleep Apnea Syndrome: 2 people, 14.29%
Intervertebral Disc Protrusion (spinal disc protrusion): 2 people, 14.29%
Herniated Nucleus Pulposus (Slipped Disk): 2 people, 14.29%
Hepatic Cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue): 2 people, 14.29%
Diabetic Neuropathy (neuropathic disorders that are associated with diabetes mellitus): 2 people, 14.29%
Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it): 2 people, 14.29%
Cushing's Syndrome (obesity, a rounded face, increased fat): 2 people, 14.29%
Sleep Disorder: 1 person, 7.14%
Hiv Infection: 1 person, 7.14%
Hepatitis C: 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Xifaxan and have Nightmares?

- Check whether Nightmares is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Xifaxan:

Xifaxan (16,609 reports)

Nightmares treatments and more:

Nightmares (42,077 reports)

Browse all side effects of Xifaxan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Nightmares:

Nightmares (1,337 drugs)

Browse all the conditions that are associated with Nightmares:

Nightmares (1,912 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on rifaximin (the active ingredients of Xifaxan) and Xifaxan (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.