Xigduo xr and Hyperglycemia - a phase IV clinical study of FDA data

Summary:

Hyperglycemia is reported as a side effect among people who take Xigduo xr (dapagliflozin propanediol; metformin hydrochloride), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Sertraline, and have Diabetes.

The phase IV clinical study analyzes which people have Hyperglycemia when taking Xigduo xr. It is created by eHealthMe based on reports of 2,877 people who have side effects when taking Xigduo xr from the FDA, and is updated regularly.

What is Xigduo xr?

Xigduo xr has active ingredients of dapagliflozin propanediol; metformin hydrochloride. eHealthMe is studying from 2,917 Xigduo xr users. Check the latest studies of Xigduo xr.

What is Hyperglycemia?

Hyperglycemia (high blood sugar) is found to be associated with 1,654 drugs and 2,497 conditions by eHealthMe. Check the latest studies of Hyperglycemia.

On Jul, 14, 2026

2,877 people reported to have side effects when taking Xigduo xr.
Among them, 76 people (2.64%) have Hyperglycemia.

Among these 76 people:

How long have people been on Xigduo xr when they have Hyperglycemia? *

What is the gender of people who have Hyperglycemia when taking Xigduo xr? *

female: 12.5 %
male: 87.5 %

What is the age of people who have Hyperglycemia when taking Xigduo xr? *

What are other drugs people take besides Xigduo xr? *

What are other side effects people have besides Hyperglycemia? *

Fatigue (feeling of tiredness): 46 people, 60.53%
High Blood Pressure: 45 people, 59.21%
High Blood Cholesterol: 43 people, 56.58%
Overdose: 34 people, 44.74%
Malignant Hypertension (Arteriolar Nephrosclerosis) (a medical condition where the blood pressure of the patient suddenly reaches extremely high): 7 people, 9.21%
Hypoglycemia (low blood sugar): 5 people, 6.58%
Heart Attack: 4 people, 5.26%
Malaise (a feeling of general discomfort or uneasiness): 4 people, 5.26%
Pollakiuria (abnormally frequent passage of relatively small quantities or urine): 3 people, 3.95%
Fascial Infection (infection in muscle surrounding tissue): 3 people, 3.95%

What are the existing conditions these people have? *

Diabetes: 52 people, 68.42%
High Blood Pressure: 46 people, 60.53%
High Blood Cholesterol: 44 people, 57.89%
Insomnia (sleeplessness): 42 people, 55.26%
Enlarged Prostate: 42 people, 55.26%
Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 41 people, 53.95%
Type 2 Diabetes: 13 people, 17.11%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 3 people, 3.95%
Gastric Mucosal Lesion (lesion of stomach mucous membrane): 3 people, 3.95%
Blood Pressure Abnormal: 2 people, 2.63%

* Approximation only. Some reports may have incomplete information.

Do you take Xigduo xr and have Hyperglycemia?

- Check whether Hyperglycemia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Xigduo xr:

Xigduo xr (2,917 reports)

Hyperglycemia treatments and more:

Hyperglycemia (48,691 reports)

How severe was Hyperglycemia and when was it recovered:

Hyperglycemia in Xigduo xr

Expand to all the drugs that have ingredients of dapagliflozin propanediol; metformin hydrochloride:

Hyperglycemia and drugs with ingredients of dapagliflozin propanediol; metformin hydrochloride (67 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Xigduo xr:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hyperglycemia:

Hyperglycemia (1,654 drugs)

Browse all the conditions that are associated with Hyperglycemia:

Hyperglycemia (2,497 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on dapagliflozin propanediol; metformin hydrochloride (the active ingredients of Xigduo xr) and Xigduo xr (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.