Xolair and Hip joint replacement - a phase IV clinical study of FDA data

Summary:

Hip joint replacement is reported as a side effect among people who take Xolair (omalizumab), especially for people who are male, 50-59 old, also take Symbicort, and have Depression.

The phase IV clinical study analyzes which people have Hip joint replacement when taking Xolair. It is created by eHealthMe based on reports of 77,224 people who have side effects when taking Xolair from the FDA, and is updated regularly.

What is Xolair?

Xolair has active ingredients of omalizumab. It is often used in asthma. eHealthMe is studying from 77,555 Xolair users. Check the latest studies of Xolair.

What is Hip joint replacement?

Hip joint replacement is found to be associated with 857 drugs and 1,063 conditions by eHealthMe. Check the latest studies of Hip joint replacement.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 31, 2026

77,224 people reported to have side effects when taking Xolair.
Among them, 31 people (0.04%) have Hip joint replacement.

Could Xolair cause Hip joint replacement?

Among these 31 people:

What is the gender of people who have Hip joint replacement when taking Xolair? *

female: 14.81 %
male: 85.19 %

What is the age of people who have Hip joint replacement when taking Xolair? *

What are other drugs people take besides Xolair? *

Symbicort: 17 people, 54.84%
Paxil: 7 people, 22.58%
Acetaminophen: 3 people, 9.68%
Epinephrine: 3 people, 9.68%
Albuterol Sulfate: 3 people, 9.68%
Tizanidine Hydrochloride: 2 people, 6.45%
Hydroxyzine Hydrochloride: 2 people, 6.45%
Heparin: 2 people, 6.45%
Gabapentin: 2 people, 6.45%
Firazyr: 2 people, 6.45%

What are other side effects people have besides Hip joint replacement? *

Blood Test Abnormal: 15 people, 48.39%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 15 people, 48.39%
High Blood Pressure: 15 people, 48.39%
Depression: 15 people, 48.39%
Panic Disorder: 15 people, 48.39%
Joint Dislocation (a joint position is changed from normal position): 9 people, 29.03%
Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 3 people, 9.68%
Hypersensitivity: 3 people, 9.68%
Nasal Disorder (diseases of nose): 3 people, 9.68%
Osteoporosis (bones weak and more likely to break): 3 people, 9.68%

What are the existing conditions these people have? *

Depression: 15 people, 48.39%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 6.45%
Hereditary Angioedema (recurrent episodes of severe swelling): 2 people, 6.45%
Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it): 2 people, 6.45%
Allergic Rhinitis: 2 people, 6.45%
Systemic Mastocytosis (a condition caused by the accumulation of mast cells in more than one part of the body): 1 person, 3.23%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 1 person, 3.23%
Psoriasis (immune-mediated disease that affects the skin): 1 person, 3.23%
Primary Immunodeficiency Syndrome: 1 person, 3.23%
Heart Disease: 1 person, 3.23%

* Approximation only. Some reports may have incomplete information.

Do you take Xolair and have Hip joint replacement?

- Check whether Hip joint replacement is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Xolair:

Xolair (77,555 reports)

Browse all side effects of Xolair:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hip joint replacement:

Hip joint replacement (857 drugs)

Browse all the conditions that are associated with Hip joint replacement:

Hip joint replacement (1,063 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on omalizumab (the active ingredients of Xolair) and Xolair (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.