Xopenex and Sinus headache - a phase IV clinical study of FDA data

Summary:

Sinus headache is reported as a side effect among people who take Xopenex (levalbuterol hydrochloride), especially for people who are female, 60+ old, also take Xanax, and have Cystic fibrosis.

The phase IV clinical study analyzes which people have Sinus headache when taking Xopenex. It is created by eHealthMe based on reports of 13,420 people who have side effects when taking Xopenex from the FDA, and is updated regularly.

What is Xopenex?

Xopenex has active ingredients of levalbuterol hydrochloride. It is often used in asthma. eHealthMe is studying from 13,816 Xopenex users. Check the latest studies of Xopenex.

What is Sinus headache?

Sinus headache (headache caused by sinus infections) is found to be associated with 690 drugs and 792 conditions by eHealthMe. Check the latest studies of Sinus headache.



On Jul, 15, 2026

13,420 people reported to have side effects when taking Xopenex.
Among them, 15 people (0.11%) have Sinus headache.

Could Xopenex cause Sinus headache?

Among these 15 people:

What is the gender of people who have Sinus headache when taking Xopenex? *

  • female: 86.67 %
  • male: 13.33 %

What is the age of people who have Sinus headache when taking Xopenex? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 11.11 %
  • 30-39: 33.33 %
  • 40-49: 0.0 %
  • 50-59: 0.0 %
  • 60+: 55.56 %

What are other drugs people take besides Xopenex? *

  1. Imitrex: 4 people, 26.67%
  2. Xanax: 4 people, 26.67%
  3. Neurontin: 3 people, 20.00%
  4. Advair Hfa: 3 people, 20.00%
  5. Spiriva: 3 people, 20.00%
  6. Medrol: 3 people, 20.00%
  7. Singulair: 3 people, 20.00%
  8. Pulmozyme: 3 people, 20.00%
  9. Nexium: 3 people, 20.00%
  10. Epipen: 3 people, 20.00%

What are other side effects people have besides Sinus headache? *

  1. Nausea (feeling of having an urge to vomit): 5 people, 33.33%
  2. Oropharyngeal Pain: 5 people, 33.33%
  3. Fatigue (feeling of tiredness): 5 people, 33.33%
  4. Nausea And Vomiting: 4 people, 26.67%
  5. Abdominal Pain Upper: 4 people, 26.67%
  6. Itching: 4 people, 26.67%
  7. Dizziness: 3 people, 20.00%
  8. Dry Mouth: 3 people, 20.00%
  9. Paranasal Sinus Discomfort: 3 people, 20.00%
  10. Dyspnea (difficult or laboured breathing): 3 people, 20.00%

What are the existing conditions these people have? *

  1. Cystic Fibrosis (disease of the secretary glands): 4 people, 26.67%
  2. Pneumonia: 2 people, 13.33%
  3. Wheezing (a high-pitched whistling sound made while you breath): 1 person, 6.67%
  4. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 6.67%
  5. Immunodeficiency Common Variable: 1 person, 6.67%
  6. Hypersensitivity: 1 person, 6.67%
  7. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 1 person, 6.67%
  8. Allergic Rhinitis: 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Xopenex and have Sinus headache?

- Check whether Sinus headache is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Xopenex:

Sinus headache treatments and more:

How severe was Sinus headache and when was it recovered:

Expand to all the drugs that have ingredients of levalbuterol hydrochloride:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Xopenex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Sinus headache:

Browse all the conditions that are associated with Sinus headache:


How the study uses the data?

The study uses data from the FDA. It is based on levalbuterol hydrochloride (the active ingredients of Xopenex) and Xopenex (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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